头颈部木村病1例并文献复习

doi:10.6040/j.issn.1673-3770.0.2023.453

摘要/Abstract

摘要： 目的探讨木村病(kimura's disease,KD)的相关诊疗方法及临床特点。方法回顾性分析1例就诊于山西医科大学第一医院KD患者的病历资料,并查阅相关文献,总结其发病特点、临床表现、组织学及影像学表现以及相关诊疗方法。结果本例患者可见右侧头颈部无痛性肿物,化验示嗜酸性粒细胞百分比23.6%,嗜酸性粒细胞绝对值1.90×10⁹/L,血清免疫球蛋白E(Immunoglobulin E, IgE)109.0 kU/L。穿刺病理结果提示KD,行手术切除肿物,随访期间无复发。结论 KD的罕见及其表现使其难以诊断,当患者出现无痛性头颈部肿块,且伴随外周血嗜酸性粒细胞增多、IgE水平升高时应考虑KD。手术切除可兼具治疗与诊断作用。

关键词: 木村病, 嗜酸性粒细胞增多症, 头颈部, 免疫球蛋白E

Abstract: Objective To study and explore the related diagnosis and treatment methods and clinical characteristics of kimura's disease(KD). Methods We retrospectively analyzed the medical records of a patient with KD in the First Hospital of Shanxi Medical University, and reviewed the relevant literature to summarize its pathogenesis, clinical manifestations, histological and imaging manifestations, and related diagnostic and therapeutic methods. Results In this case, a painless mass was seen in the right side of the head and neck, and the laboratory tests showed that the percentage of eosinophils was 23.6%, the absolute value of eosinophils was 1.90×10⁹/L, and the serum immunoglobulin E(IgE)was 109.0 kU/L. The puncture pathology results suggested that the KD was present, and surgical resection of the mass was performed, and there was no recurrence during the follow up period. Conclusion The rarity of KD and its manifestations make it difficult to diagnose, but KD should be considered when patients present with painless head and neck masses accompanied by eosinophilia in the peripheral blood and elevated levels of IgE. Surgical excision can be both therapeutic and diagnostic.

Key words: Kimura disease, Eosinophilia, Head and neck, Immunoglobulin E

中图分类号:

R739.91

尹振乾,皇甫辉. 头颈部木村病1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(5): 104-107.

YIN Zhenqian, HUANGFU Hui. Kimura disease:a case report and literature review[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(5): 104-107.

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