Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (1): 86-91.doi: 10.6040/j.issn.1673-3770.0.2020.157

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Relationship between serum procalcitonin level of tumor-bearing mice and medullary thyroid carcinoma

ZENG Bo, TIAN Xingde   

  1. Department of Otolaryngology & Head and Neck Surgery, the First Affiliated Hospital of Yangtze University, Jingzhou 434000, Hubei,  China
  • Published:2021-02-01

Abstract: Objective To study the relationship between serum procalcitonin(PCT)and calcitonin(CT)levels in medullary thyroid carcinoma(MTC). Methods We evaluated the serum PCT and CT levels, tumor weight and volume, and bodyweight using MTC mice models to ascertain the relationship between serum PCT and CT and tumors. Results Serum PCT and CT in the group A mice were significantly and positively correlated with tumor weight; serum PCT and CT were also positively correlated. Conclusions This experiment demonstrates that serum PCT may be used as a tumor marker for MTC, in addition to serum CT, which has demonstrated utility for the diagnosis of MTC.

Key words: Medullary thyroid carcinoma, Procalcitonin, Calcitonin, Serum, Level, Mice

CLC Number: 

  • R762
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