Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (4): 115-122.doi: 10.6040/j.issn.1673-3770.0.2020.354

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The pathomechanism and treatment progress of trigeminal neuralgia

XU Feifei1,WU Hao2   

  1. 1. Nantong University Medical School, Nantong 226001, Jiangsu, China;
    2. Department of Otolaryngology & Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China
  • Published:2021-08-05

Abstract: Trigeminal neuralgia(TN)is the most common craniofacial pain, but its pathogenesis has not been fully understood. TN often manifests as a sudden, severe, brief, stabbing, and recurrent pain in one or more branches of the trigeminal nerve. Classification methods, various pathogenesis(such as central hypothesis, nerve compression theory, inflammatory response theory, bioresonance hypothesis, and ion channel alteration theory)and clinical multidisciplinary treatment progress were reviewed to provide references for personalized treatment of TN.

Key words: Trigeminal neuralgia, Classification, Mechanism, Ion channel, Treatment

CLC Number: 

  • R76
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