Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (3): 50-55.doi: 10.6040/j.issn.1673-3770.0.2021.533

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Eosinophils and Olfactory Dysfunction

YI RuonanOverview,CHEN Fuquan   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, Xijing Hospital, Air Force Military Medical University, Xi'an 710032, Shaanxi, China
  • Published:2022-06-15

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Abstract: Chronic rhinosinusitis(CRS)is a refractory disease with a very complex pathogenesis. Olfactory dysfunction is an important clinical symptoms of CRS.Despite drug and surgical intervention, the recurrence rate of CRS is high, and the olfactory dysfunction of patients sometimes cannot be improved, which may seriously affects a patient's quality of life.Eosinophils(EOS)are an important cell type.The degradation and accumulation of eosinophils, the release of cytokines and mucus secretion play important roles in the pathogenesis of different types of chronic rhinosinusitis. While many scholars consider that tissue EOS to be closely related to olfactory dysfunction caused by peripheral blood EOS and CRS, but some scholars hold different views.

Key words: Eosinophils, Olfactory dysfunction, Chronic rhinosinusitis, Olfactory Mucosa

CLC Number: 

  • R765.4
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