Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2025, Vol. 39 ›› Issue (5): 104-107.doi: 10.6040/j.issn.1673-3770.0.2023.453

• Original Article • Previous Articles    

Kimura disease:a case report and literature review

YIN Zhenqian1, HUANGFU Hui2   

  1. 1. First Clinical Medical College, Shanxi Medical University, Taiyuan 03000, Shanxi, China2. Department of Otorhinolaryngology & Head and Neck Surgery, The Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
  • Published:2025-09-19

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Abstract: Objective To study and explore the related diagnosis and treatment methods and clinical characteristics of kimura's disease(KD). Methods We retrospectively analyzed the medical records of a patient with KD in the First Hospital of Shanxi Medical University, and reviewed the relevant literature to summarize its pathogenesis, clinical manifestations, histological and imaging manifestations, and related diagnostic and therapeutic methods. Results In this case, a painless mass was seen in the right side of the head and neck, and the laboratory tests showed that the percentage of eosinophils was 23.6%, the absolute value of eosinophils was 1.90×109/L, and the serum immunoglobulin E(IgE)was 109.0 kU/L. The puncture pathology results suggested that the KD was present, and surgical resection of the mass was performed, and there was no recurrence during the follow up period. Conclusion The rarity of KD and its manifestations make it difficult to diagnose, but KD should be considered when patients present with painless head and neck masses accompanied by eosinophilia in the peripheral blood and elevated levels of IgE. Surgical excision can be both therapeutic and diagnostic.

Key words: Kimura disease, Eosinophilia, Head and neck, Immunoglobulin E

CLC Number: 

  • R739.91
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