JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (1): 55-63.doi: 10.6040/j.issn.1673-3770.0.2017.047

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Meta-analysis of the uvulopalatopharyngoplasty(UPPP)and modified UPPP for obstructive sleep apnea hypopnea syndrome.

  

  1. Department of Otorhinolaryngology, 1. Affiliated Jiangning Hospital, Nanjing Medical University, Nanjing 211100, Jiangsu, China;2. Department of Otolaryngology, the First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China
  • Received:2017-02-07 Online:2017-02-16 Published:2017-02-16

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Abstract: Objective To assess the efficacy of various soft palate surgeries for obstructive sleep apnea hypopnea syndrome(OSAHS). Methods Clinical studies of the soft palate surgical procedures for OSAHS were searched in databases including Cochrane, MEDLINE and PubMed, from their inception to October, 2015. References of the selected studies then underwent retrospective review and citation retrieval. Two reviewers independently screened the articles according to the predefined inclusive and exclusive criteria, and then extracted necessary data and evaluated quality of the included studies. A meta-analysis was performed using RevMan 5.1.0. Results A total of 20 self-controlled trials or RCTs involving 631 patients(88% males)were finally included. Quality evaluation was conducted independently by the two reviewers and crosschecked. Polysomnograph was adopted as a diagnostic criterion, but subjective assessment was used often for the evaluations of obstructive sites. Meta-analyses showed a significant improvement in apnea hyponea index(AHI), lowest saturation(LSAT)and Epworth sleepiness scale score(ESS). Sensitivity analysis indicated that these results were stable. Conclusion High-quality studies as well as objective indicators for the evaluation of obstructive sties are still needed. The soft palate surgeries are effective in reducing AHI and ESS, and enhancing LSAT. To date, no evidence has suggested one surgical approach is more effective than the others.

Key words: Modified uvulopalatopharyngoplasty, Soft palate, Meta-analysis, Sleep apnea, obstructive, Uvulopalatopharyngoplasty, Snoring

CLC Number: 

  • R766.7
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