JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2018, Vol. 32 ›› Issue (3): 54-57.doi: 10.6040/j.issn.1673-3770.0.2017.422

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Clinical significance of eosinophils and neutrophils in blood and allergic reaction in patients with chronic rhinosinusitis

ZHANG Jie1, GONG Qi2   

  1. Department of Otolaryngology, Dachang Hospital of Baoshan District of Shanghai, Shanghai 200436, China;
  • Received:2017-10-12 Online:2018-05-20 Published:2018-05-20

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Abstract: Objective To analyze the percentage of eosinophils and neutrophils in the blood of patients with chronic rhinosinusitis(CRS)and clinical differences in allergic reactions. Methods We prospectively selected 150 patients with CRS treated in Baoshan District Dacheng Hospital in Shanghai and Dawn Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from May 2015 to May 2017. Clinical data and skin prick test results were collected, and the ratio of neutrophils and eosinophils in the blood, and their association with the onset of CRS, were analyzed. Results The pathological diagnosis showed that 45 cases were neutrophilic and 105 cases were eosinophilic. The percentage of eosinophilic granulocytes in the blood of patients with infiltrating eosinophils was significantly higher than that in the blood of patients with infiltrating neutrophils(P < 0.05). There were no significant differences in the distribution of CRS without nasal polyps, CRS with nasal polyps, and immunopathological features between the two groups of infiltrated patients(P>0.05). Conclusion The degree of infiltration of neutrophils and eosinophils in the pathological tissues of CRS patients was related to the ratio of eosinophils in the blood, and the degree of infiltration of local eosinophils and peripheral blood eosinophils appeared to be consistent.

Key words: Neutrophils, Nasal polyps, Eosinophils, Rhinosinusitis, chronic

CLC Number: 

  • R765.4
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