Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (6): 83-88.doi: 10.6040/j.issn.1673-3770.0.2021.249

• 论著 • Previous Articles    

Application of combining fiberoptic endoscopic evaluation of swallowing technology and swallowing quality of life scale in patients with dysphagia after chemoradiotherapy for nasopharyngeal carcinoma

REN Jia1, LÜ Dan1, ZHANG Yin2, SUN Jiali3, MA Lan4, ZHENG Yitao1, YANG Jimin1, YU Lingyu1, LI Bo1   

  1. 1. Department of Otolarynology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China;
    2. Rehabilitation Medical Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China;
    3. Department of Otolarynology Head and Neck Surgery, The Third People's Hospital of Chengdu, Chengdu 610031, Sichuan, China;
    4. Department of Otolarynology Head and Neck Surgery, Chongqing People's Hospital, Chongqing 401121, China
  • Published:2022-12-07

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Abstract: Objective to evaluate the post-chemoradiotherapy quality of life of nasopharyngeal carcinoma patients with dysphagia using the swallowing quality of life(SWAL-QOL)scale and fiberoptic endoscopic evaluation of swallowing(FEES)in order to expand the clinical applications. Methods A total of 162 nasopharyngeal carcinoma patients meeting the inclusion criteria were enrolled as the patient group in the West China Hospital from September 2019 to April 2020, who had received chemoradiotherapy and were with dysphagia problem. Additionally, 144 individuals without relevant problems were recruited as the control group. All the participants were asked to fill the SWAL-QOL scale, and 96 individuals from the patient group received further FEES examination and were graded by the Penetration-Aspiration Scale(PAS). Results Participants in patient group had significantly lower total scores(124.69±25.57)and swallowing symptoms subscale scores(58.56±9.46)than those in control group(P<0.05). In the quality of life subscale, except for the two dimensions of “fatigue” and “sleep”, the differences in other dimensions were statistically significant(P<0.05). Significant differences were presented in all other dimensions,except for “fatigue” and “sleep”. The PAS results revealed 22 patients with no penetration(22.92%), 60 patients with penetration(62.50%)and 14 patients with silent aspiration(14.58%). Significant difference was observed in the three goups, include the total scores of SWAL-QOL and the scores of 4 dimensions in the questionnaire. No significant difference was presented between groups of no penetration and penetration in the total scores of SWAL-QOL and the scores of all the dimensions in the questionnaire(P>0.05). However, significant difference was observed between groups of no penetration and silent aspiration in the total scores of SWAL-QOL and the scores of 4 dimensions in the questionnaire(P<0.05). Significant difference was observed between groups of penetration and silent aspiration in the total scores of SWAL-QOL and the scores of 2 dimensions in the questionnaire(P<0.05). Conclusion Dysphagia could affect the post- chemoradiotherapy quality of life of nasopharyngeal carcinoma patients in many aspects. Additionally, the SWAL-QOL can be used to evaluate the swallowing-related quality of life of nasopharyngeal carcinoma patients after chemoradiotherapy.

Key words: Nasopharyngeal carcinoma, Dysphagia, Swallowing quality of Life, Fiberoptic endoscopic eraluation of swallowing, Assessment

CLC Number: 

  • R856.76
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