过敏性疾病与糖尿病的相关性及潜在关联机制

doi:10.6040/j.issn.1673-3770.0.2022.411

Abstract

Abstract: Allergic diseases and diabetes mellitus(DM)are systemic chronic diseases associated with inflammation. Both conditions involve multiple organs and complex pathogenesis. However, current evidence on the relationship between allergic diseases and DM is contradictory, and there have been few reports on associated mechanisms. Most studies have reported that DM was positively associated with asthma in allergic diseases, but negatively associated with allergic rhinitis and atopic dermatitis. The different associations may be due to ethnicity and race differences. The mechanisms associated with allergic diseases and DM are not yet fully understood and may be related to pro-inflammatory pathways and blood glucose metabolism. This article reviews epidemiological and mechanistic studies related to allergic diseases and DM to enhance clinical knowledge of their co-morbidities.

Key words: Asthma, Allergic rhinitis, Atopic dermatitis, Diabetes mellitus

CLC Number:

R765

LU Gan, DENG Yuqin, TAO Zezhang. Relationship between allergic diseases and diabetes mellitus and underlying mechanisms[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(5): 215-222.

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