山东大学耳鼻喉眼学报 ›› 2013, Vol. 27 ›› Issue (1): 24-25.doi: 10.6040/j.issn.1673-3770.0.2012.163

• 论著 • 上一篇    下一篇

单唾液酸四己糖神经节苷脂钠治疗突发性耳聋临床观察

沈峰   

  1. 江苏省中医院耳鼻喉科, 南京  210029
  • 收稿日期:2012-05-11 发布日期:2013-02-16
  • 作者简介:沈峰,博士, 硕导。 E-mail:js4604@126.com

Treatment of sudden hearing loss by monosialotetrahexosylganlioside

SHEN  Feng   

  1. Department of Otorhinolaryngology, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing 210029, China
  • Received:2012-05-11 Published:2013-02-16

摘要:

目的   探讨单唾液酸四己糖神经节苷脂钠治疗突发性耳聋的疗效。方法   将突发性耳聋患者80例随机分为治疗组和对照组,治疗组患者给予单唾液酸四己糖神经节苷脂钠静滴,对照组患者给予甲钴胺注射液静推,两组均同时行激素、扩血管药物、高压氧等治疗。10d为一疗程。结果   单唾液酸四己糖神经节苷脂钠组听力提高的总有效率为85%,痊愈率为52.5%;而对照组的总有效率为62.5%,痊愈率为27.5%,两组差异有统计学意义(P<0.05);治疗组耳鸣好转的总有效率为80%,对照组的总有效率为51.7%, 两组差异有统计学意义(P<0.05)。结论   单唾液酸四己糖神经节苷脂钠治疗突发性耳聋疗效相对于其他方法疗效较好。

关键词: 单唾液酸四己糖神经节苷脂钠, 耳鸣, 突发性耳聋

Abstract:

Objective   To investigate the efficacy of monosialotetrahexosylganlioside in the treatment of sudden hearing lossl. Methods   80 cases suffered from sudden hearing loss were randomly divided into 2 groups. Except for glucocorticoid plus vasodilators and hyperbaric oxygen therapy, 40 cases in the treatment group were administrated with monosialotetrahexosylganlioside, while the other 40 cases in the control group were given mecobalamin injection. One course lasted for 10 days. Results   The total effective rates of hearing improvement between the treatment group and control group were 85% and 62.5%, while the cure rates of both groups were 52.5% and 27.5%(P<0.05).  Meanwhile, the total effective rate of tinnitus in the treatment and control group were 80% and 51.7%(P<0.05). Conclusion   Monosialotetrahexosylganlioside plays a positive role in the treatment of sudden hearing loss.

Key words: Monosialotetrahexosylganlioside, Tinnitus, Sudden hearing loss

中图分类号: 

  • R764
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