急性视网膜坏死综合征临床治疗42眼

山东大学耳鼻喉眼学报

急性视网膜坏死综合征临床治疗42眼

董卫红¹,周芳²,毕宏生¹,王兴荣¹,杜秀娟¹,马先祯¹,俞超¹

1. 山东中医药大学眼科中心，山东施尔明眼科医院，济南 250002；
2. 山东大学齐鲁医院眼科，济南 250012

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-10-16 发布日期:2008-10-16
通讯作者: 周芳

Acute retinal necrosis syndrome in 42 eyes

DONG Wei-hong¹, ZHOU Fang², BI Hong-sheng¹, WANG Xing-rong¹,
DU Xiu-juan¹, MA Xian-zhen¹, YU Chao¹

1. Eye Center, Shandong University of Traditional Chinese Medicine,
Shandong Shierming Eye Hospital, Jinan 250002, China;
2. Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250012, China

Received:1900-01-01 Revised:1900-01-01 Online:2008-10-16 Published:2008-10-16
Contact: ZHOU Fang

摘要/Abstract

摘要： 目的探讨急性视网膜坏死综合征(ARNS)的治疗方法并评价其治疗效果。方法对急性视网膜坏死综合征42眼进行药物、激光及手术综合治疗。所有患者均给予无环鸟苷及糖皮质激素治疗，对于药物治疗病情无好转或就诊时已有严重玻璃体混浊或已并发视网膜脱离患者，及时行玻璃体视网膜联合手术。随访6～24个月，分析其治疗效果。结果42眼炎症均得到有效控制，单眼发病患者对侧眼未出现发病。37眼视力有不同程度改善,其中23眼视力≥0.1，最好视力为0.8。40眼视网膜完全复位，部分复位1眼。结论急性视网膜坏死综合征是一种严重致盲性眼病，早期易被误诊，视网膜脱离是其常见的严重并发症。早期足量的抗病毒、皮质类固醇激素的应用以及玻璃体视网膜联合手术是治疗急性视网膜坏死综合征的有效方法。

关键词: 急性视网膜坏死, 视网膜脱离, 玻璃体切除

Abstract: To explore the therapeutic methods for acute retinal necrosis syndrome and to evaluate the therapeutic effects of anti-virus drugs, photocoagulation and vitreous-retinal surgery. MethodsThirty-six cases (42 eyes) of acute retinal necrosis syndromes were studied. All were treated with acyclovir （ACV） and corticoid hormones. Those with severe vitreous inflammation or retinal detachment were treated with drugs, and photocoagulation in combination with surgery. Followed up from 6 to 24 months, the retinas and eyesight were observed. ResultsThe retinas of 40 eyes were all successfully reattached, and the visual acuity of 37 eyes was improved, in which the acuity of 23 eyes was better than 0.1 and the best acuity was 0.8. ConclusionRetinal detachment is the most severe complication of acute retinal necrosis syndrome, and it can lead to visual loss and often is easily misdiagnosed. If it is diagnosed early and treated in time with proper methods such as effective drugs including acyclovir and corticoid hormones, photocoagulation and vitreous-retinal surgery, good results can be produced.

Key words: Retinal detachment, Vitrectomy, Acute retinal necrosis syndrome

中图分类号:

R774.1

董卫红,周芳,毕宏生,王兴荣,杜秀娟,马先祯,俞超 . 急性视网膜坏死综合征临床治疗42眼[J]. 山东大学耳鼻喉眼学报, 2008, 22(5): 457-459 .

DONG Wei-hong,ZHOU Fang,BI Hong-sheng,WANG Xing-rong,
DU Xiu-juan,MA Xian-zhen,YU Chao . Acute retinal necrosis syndrome in 42 eyes[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(5): 457-459 .

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