患者管理方式对变应性鼻炎舌下含服粉尘螨滴剂疗效的影响

doi:10.6040/j.issn.1673-3770.0.2018.044

摘要/Abstract

摘要： 目的分析不同管理方式对接受舌下含服粉尘螨滴剂治疗(SLIT)的变应性鼻炎患者治疗1年后的依从性和疗效的影响,以探寻一种较好的患者管理方法确保患者完成标准疗程及获得更好的疗效。方法 180例接受舌下含服粉尘螨滴剂治疗的变应性鼻炎患者随机分为自媒体管理组(A组 90 例)和电话管理组(B组 90例)。A组建立医患微信和(或)QQ群,并成立由课题组专职医生任组长的自媒体管理小组,制订每个月的健康教育计划、每周向群内发送3次以上SLIT相关知识、及时评估患者报告结果。B组进行现场示范和教育,治疗开始后每3个月电话随访一次并进行相应的指导教育。统计分析治疗1年后两组的依从性及疗效情况。结果治疗1年内,A组脱落率为13.3%(12/90),B组脱落率为32.2%(29/90),两组间差异有统计学意义(χ2=9.128,P=0.003)。A、B两组组内比较,治疗前后各症状评分差异有统计学意义(P<0.05)。A、B两组组间比较,治疗前各症状评分差异无统计学意义(P>0.05),治疗后各症状评分差异有统计学意义(P<0.05)。A组显效15 例(16.67%),好转49例(54.44%),无效26 例(28.89%),总有效率为71.11%。B组显效13 例(14.44%),好转26例(28.89%),无效51 例(56.67%),总有效率为43.33%。结论自媒体管理有助于提高AR患者接受舌下含服粉尘螨滴剂治疗的依从性和疗效,特别是在长期治疗中更有优势。

关键词: 依从性, 患者管理, 自媒体, 变应性鼻炎, 舌下免疫治疗, 疗效

Abstract: Objective To analyze the influence of different patient management methods on the clinical effect and compliance to treatment with sublingual dermatophagoides farinae drops in patients with allergic rhinitis(AR). Methods One hundred and eighty patients with AR were randomly divided into a We-Media management Group(Group A, 90 patients)and a telephone management group(Group B, 90 patients). All patients were treated with sublingual immunotherapy(SLIT). In Group A, doctor-patient WeChat and/or QQ groups were formed. The doctor in charge acted as group leader, prepared monthly plans, sent to the patients SLIT-related information more than 3 times a week, and assessed patient reported outcome. In Group B, the patients were provided with on-the-spot demonstration and explanation and were followed up by telephone once every 3 month. We statistically analyzed dropout rates and the curative effect in the two groups at 1 year. Results The dropout rate in groups A and B was 13.3%(12/90)and 32.2%(29/90), respectively and the difference was statistically significant(χ2=9.128,P=0.003). The symptom scores before and after treatment were significantly different in both groups(P<0.05). There was no significant difference between Groups A and B before treatment(P>0.05), while the difference in the score of each symptom between the groups after treatment was significant(P<0.05). In Group A, the results were markedly effective in 15 patients(16.67%), effective in 49(54.44%), and ineffective in 26(28.89%), with a general effective rate of 71.11%(64/90). In Group B, the results were markedly effective in 13 patients(14.44%), effective in 26(28.89%), and ineffective in 51(56.67%), with a general effective rate of 43.33%(39/90). Conclusion The clinical effect and treatment compliance can be improved in patients with AR receiving SLIT by We-Media management.We-Media management is more advantageous especially in the long-term.

Key words: Allergic rhinitis, Sublingual immunotherapy, Patient management, We-Media, Clinical effect, Compliance

中图分类号:

R765.4

吴湘萍. 患者管理方式对变应性鼻炎舌下含服粉尘螨滴剂疗效的影响[J]. 山东大学耳鼻喉眼学报, 2018, 32(3): 68-72.

WU Xiangping. Influence of patient management on the clinical effect of sublingual dermatophagoides farinae drops in patients[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 68-72.

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