山东大学耳鼻喉眼学报 ›› 2023, Vol. 37 ›› Issue (4): 1-12.doi: 10.6040/j.issn.1673-3770.0.2023.137
• 耳鸣临床与中枢神经网络机制的研究前沿及进展——述评 •
陈倬诣,郑亿庆,杨海弟
CHEN Zhuoyi, ZHENG Yiqing, YANG Haidi
摘要: 慢性主观性耳鸣是耳鼻喉科较为常见的症状,其发病率高且临床表现多样,病理机制亦较为复杂。耳鸣的分类和相关神经生理机制研究是指导耳鸣临床诊断和个体化精准医疗的基础。近年来,越来越多的耳鸣研究在上述领域提出了新的思路。新的证据显示,耳鸣的特征维度变化可能比亚型分类更能准确地解释耳鸣的异质性,在临床研究与诊疗方面具有巨大的应用潜力。此外,耳鸣新的网络模型整合了耳鸣本身及其合并症神经生理机制,进一步发展和完善了个体化治疗的理论基础。论文重点总结了耳鸣分类的维度网络模型和耳鸣合并症的三网络模型,并结合最新的指南更新和循证医学证据,对常见的耳鸣治疗方法进行简要概述。
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