Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (2): 7-14.doi: 10.6040/j.issn.1673-3770.0.2022.418

• 论著 • Previous Articles    

Prognosis and influencing factors in sudden deafness patients with acoustic stapedius reflex threshold

SUN Yongqiang1,2, SONG Zhongyi2, WANG Chunfang2, LI Xiao2, FU Ying2, PAN Xinliang1,2   

  1. 1. Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China;
    2. Department of Otorhinolaryngology & Head and Neck Surgery, Qilu Hospital of Shandong University(Qingdao), Qingdao 266035, Shandong, China
  • Published:2023-03-30

PDF (PC)

384

Abstract: Objective Analyze the prognosis of sudden deafness patients with acoustic stapedius reflex threshold and explore its influencing factors. Methods This study was a retrospective analysis of the clinical data of 282 patients who suffered sudden deafness with acoustic stapedius reflex threshold from January 2018 to December 2021. Excel was used for data processing, and SPSS 26.0 was used for descriptive and statistical analysis of the collected data. Statistical analyses were conducted on factors such as gender, age, time of medical treatment, tinnitus, vertigo, basic diseases(diabetes, hypertension, coronary heart disease), hearing curve type, degree of hearing loss, acoustic stapedius reflex threshold, difference between acoustic stapedius reflex threshold and hearing threshold(A-T). Results Among 282 cases of sudden deafness with acoustic stapedius reflex threshold, 101 cases were cured, 8 cases were markedly effective, 54 cases were effective, and 119 cases were ineffective. The total effective rate was 57.8%. Deafness side(P=0.907), accompanying symptoms(Pvertigo=0.686, Ptinnitus=0.534), basic diseases(Phypertension= 0.338, Pdiabetes=0.262, Pcoronary heart disease=0.780), acoustic stapedius reflex threshold(P0.5 kHz=0.152, P1.0 kHz=0.701, P2.0 kHz=0.810), the difference between acoustic stapedius reflex threshold and the pure tone hearing threshold(P0.5 kHz A-T=0.413,P2 kHz A-T=0.092)of patients who suffered sudden deafness with acoustic stapedius reflex threshold had no significant difference in prognosis. However, age(P=0.022), sex(P=0.001), visit time of sudden deafness(P<0.001), type of hearing curve(P=0.004), degree of hearing loss(P=0.008)and difference between 1 kHz acoustic stapedius reflex threshold and hearing threshold(P1 kHz A-T<0.001)were effective prognostic factors. Conclusion In sudden deafness patients with acoustic stapedius reflex threshold, gender, age, visit time of sudden deafness, type of hearing curve, degree of hearing loss and difference between 1 kHz acoustic stapedius reflex threshold and hearing threshold have an impact on the prognosis of deafness. The change of acoustic stapedius reflex threshold has no significant correlation with the prognosis of sudden deafness patients. However, the effect of sudden deafness patients can be estimated by the 1 kHz acoustic stapedius reflex threshold and hearing threshold difference to improve patients confidence in treatment.

Key words: Sudden deafness, Prognosis, Acoustic stapedius reflex, Acoustic stapedius reflex threshold

CLC Number: 

  • R764.43
[1] 中华耳鼻咽喉头颈外科杂志编辑委员会,中华医学会耳鼻咽喉头颈外科学分会.突发性聋诊断和治疗指南(2015)[J].中华耳鼻咽喉头颈外科杂志, 2015, 50(6): 443-447. doi:10.3760/cma.j.issn.1673-0860.2015.06.002
[2] 伦杰, 张亚楠, 薛建军. 突发性耳聋患者临床治疗效果及相关影响因素分析[J]. 中国耳鼻咽喉颅底外科杂志, 2016, 22(3): 198-202. doi:10.11798/j.issn.1007-1520.201603006 LUN Jie, ZHANG Yanan, XUE Jianjun. Analysis of clinical therapeutic effect and related influencing factors in patients with sudden deafness[J]. Chinese Journal of Otorhinolaryngology-Skull Base Surgery, 2016, 22(3): 198-202. doi:10.11798/j.issn.1007-1520.201603006
[3] 宋攀攀, 何静静, 沈珊珊, 等. 不同阶段突发性耳聋患者焦虑、抑郁的调查[J]. 医学研究杂志, 2013, 42(5): 56-60. doi:10.3969/j.issn.1673-548X.2013.05.017 SONG Panpan, HE Jingjing, SHEN Shanshan, et al. Anxiety and depression survey in different stages of patients with sudden hearing loss[J]. Journal of Medical Research, 2013, 42(5): 56-60. doi:10.3969/j.issn.1673-548X.2013.05.017
[4] Jack Katz. 临床听力学[M]. 北京:人民卫生出版社, 2006: 179-185.
[5] Shi L, Zhao R, Li XX, et al. A review of the neurobiological mechanisms that distinguish between loudness recruitment and hyperacusis[J]. Med Sci Monit, 2022, 28: e936373. doi:10.12659/MSM.936373
[6] Preyer S, Gummer AW. Nonlinearity of mechanoelectrical transduction of outer hair cells as the source of nonlinear basilar-membrane motion and loudness recruitment[J]. Audiol Neurootol, 1996, 1(1): 3-11. doi:10.1159/000259185.
[7] Zhang MS, Zwislocki JJ. OHC response recruitment and its correlation with loudness recruitment[J]. Hear Res, 1995, 85(1/2): 1-10. doi:10.1016/0378-5955(95)00026-Z
[8] 余茜, 左汶奇, 钟时勋. 平坦下降型突发性聋患者耳蜗电图与预后的关系研究[J]. 听力学及言语疾病杂志, 2021, 29(6): 663-667. doi:10.3969/j.issn.1006-7299.06.015 YU Qian, ZUO Wenqi, ZHONG Shixun. Correlation between electrocochleogram and prognosis in patients with sudden deafness of Flat type[J]. Journal of Audiology and Speech Pathology, 2021, 29(6): 663-667. doi:10.3969/j.issn.1006-7299.06.015
[9] 张呈辉. 突聋患者耳蜗电图与预后的关系[J]. 听力学及言语疾病杂志, 2016, 24(3): 288-290. doi:10.3969/j.issn.1006-7299.2016.03.018 ZHANG Chenghui. Relationship between cochlear electrogram and prognosis in patients with sudden deafness[J]. Journal of Audiology and Speech Pathology, 2016, 24(3): 288-290. doi:10.3969/j.issn.1006-7299.2016.03.018
[10] 梁思玉, 肖其珍, 陈果, 等. 1 000 Hz阈值对评估低频型突发性聋预后的临床意义[J]. 中华耳科学杂志, 2020, 18(6): 1034-1037. doi:10.3969/j.issn.1672-2922.2020.06.007 LIANG Siyu, XIAO Qizhen, CHEN Guo, et al. The significance of threshold at 1 000 Hz in low-frequency sudden sensorineural hearing loss[J]. Chinese Journal of Otology, 2020, 18(6): 1034-1037. doi:10.3969/j.issn.1672-2922.2020.06.007
[11] 杨仕明. 听觉损伤后毛细胞再生与聋病基因治疗策略[J]. 中华耳科学杂志, 2009, 7(4): 271-277. doi:10.3969/j.issn.1672-2922.2009.04.003 YANG Shiming. Strategies of inner ear hair cell regeneration and gene therapy for hearing loss[J]. Chinese Journal of Otology, 2009, 7(4): 271-277. doi:10.3969/j.issn.1672-2922.2009.04.003
[12] Jia SP, Yang SM, Guo WW, et al. Fate of mammalian cochlear hair cells and stereocilia after loss of the stereocilia[J]. J Neurosci, 2009, 29(48): 15277-15285. doi:10.1523/JNEUROSCI.3231-09.2009
[13] 刘佳丽, 李洪涛. 254例突发性耳聋预后的影响因素分析[J]. 陆军军医大学学报, 2022, 44(4): 385-389. doi:10.16016/j.2097-0927.202108215 LIU Jiali, LI Hongtao. Prognostic factors of sudden sensorineural hearing loss: analysis of 254 cases[J]. Journal of Army Medical University, 2022, 44(4): 385-389. doi:10.16016/j.2097-0927.202108215
[14] 周长明, 郑茜玲, 杨川, 等. 176例突发性耳聋患者的临床特征分析[J]. 中国听力语言康复科学杂志, 2017, 15(2): 111-114. doi:10.3969/j.issn.1672-4933.2017.02.009 ZHOU Changming, ZHENG Xiling, YANG Chuan, et al. The clinical characteristics of 176 patients with sudden sensorineural hearing loss[J]. Chinese Scientific Journal of Hearing and Speech Rehabilitation, 2017, 15(2): 111-114. doi:10.3969/j.issn.1672-4933.2017.02.009
[15] 冰丹,兰兰,关静,等.年龄对突发性耳聋的预后影响[J].中华耳科学杂志, 2018,16(3): 312-318. doi:10.3969/j.issn.1672-2922.2018.03.011 Bing Dan, Lan Lan, Guan Jing, et al. Age and prognosis of sudden deafness[J]. Chinese Journal of Otologists, 2018, 16(3): 312-318. doi:10.3969/j.issn.1672-2922.2018.03.011
[16] Hiroaki Sato, Shigeru Kuwashima, Shin-Ya Nishio, et al. Epidemiological survey of acute low-tone sensorineural hearing loss[J]. Acta Otolaryngol, 2017, 137: S34-S37. doi: 10.1080/00016489.2017.1297538
[17] W Maier, J Schipper. Prognostic relevance of anamnestic and diagnostic parameters in low-frequency hearing impairment [J]. J Laryngol Otol, 2006, 120(8): 613-618. doi: 10.1017/S002221510600137X
[18] Korres S, Stamatiou G A, Gkoritsa E, et al. Prognosis of patients with idiopathic sudden hearing loss: role of vestibular assessment[J]. J Laryngol Otol, 2011, 125(3): 251-257. doi: 10.1017/S0022215110002082
[19] Erdal Samim, Rahmi Kilic, Ali Ozdek, et al. Combined treatment of sudden sensorineural hearing loss with steroid, dextran and piracetam: experience with 68 cases[J]. Eur Arch Otorhinolaryngol, 2004, 261(4): 187-190. doi: 10.1007/s00405-003-0659-y
[20] A Ceylan, F Celenk, Y K Kemalo glu, et al. Impact of prognostic factors on recovery from sudden hearing loss[J]. J Laryngol Otol, 2007, 121(11):1035-1040. doi: 10.1017/S0022215107005683
[21] 梁敏, 吴悔, 陈建勇, 等. 前庭诱发肌源性电位预测突聋患者疗效的临床价值[J].山东大学耳鼻喉眼学报, 2020, 34(5): 27-32. doi:10.6040/j.issn.1673-3770.1.2020.063 Liang Min, Wu Hui, Chen Jianyong, et al. Clinical value of vestibular evoked myogenic potential to predict prognosis of idiopathic sudden sensorineural hearing loss[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 27-32. doi:10.6040/j.issn.1673-3770.1.2020.063
[22] Chengfang Chen, Guanggang Shi, Mingqiang He, et al. Characteristics and prognosis of idiopathic sudden sensorineural hearing loss in aged people: a retrospective study[J]. Acta Otolaryngol, 2019, 139(11): 959-965. doi: 10.1080/00016489.2019.1657589
[23] 付剑芬, 傅江涛, 林洪斌, 等.老年突发性耳聋流行病学特征及发病相关影响因素和预防措施分析[J].中国预防医学杂志, 2019, 20(11): 1036-1039. doi:10.16506/j.1009-6639.2019.11.006 Fu Jianfen, Fu Jiangtao, Lin Hongbin, et al. Epidemiological characteristics, risk factors and preventive measures of sudden deafness in the elderly[J]. Chinese Journal of Preventive Medicine, 2019, 20(11): 1036-1039. doi:10.16506/j.1009-6639.2019.11.006
[24] 杨安妮,李琦,李湘平.突发性聋预后研究进展[J].中华耳科学杂志, 2021, 19(2): 306-310. doi:10.3969/j.issn.1672-2922.2021.02.024 YANG Annie, LI Qi, LI Xiangping. Advances in research on prognosis of sudden sensorineural hearing loss[J]. Chinese Journal of Otologists, 2021, 19(2): 306-310. doi:10.3969/j.issn.1672-2922.2021.02.024
[25] 韩朝, 丁娟. 中耳肌肉生理及病理[J].山东大学耳鼻喉眼学报, 2019, 33(5): 6-10. doi:10.6040/j.issn.1673-3770.1.2019.038 Han Chao, Ding Juan. Physiology and pathology of middle ear muscle[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(5): 6-10. doi:10.6040/j.issn.1673-3770.1.2019.038
[1] SHI Anni, ZHANG Jiajia, BAI Peng, ZHANG Chongyang. Analysis of a therapeutic modality for sudden deafness utilizing neck acupuncture comprising seven lines of treatment [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 103-107.
[2] CHENG Yao, ZHANG Zhen, YANG Ji, FENG Chengmin, DENG Qicheng, ZHANG Xi, ZHAO Rui, ZHU Xin, WU Junzhi, LIU Hai, DENG Shishan. Expression and clinical significance of CIP2A in hypopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 40-44.
[3] LIU Pan, WANG Chuan, ZHAO Zeqi, WU Mei, XU Jifeng, LI Wei, ZHANG Weiqiang, LIU Wen. Five cases of metastatic clear cell carcinoma of the head and neck: a case report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(4): 45-50.
[4] WANG Zhongwei, YANG Lin, GUO Ya, SUN Bin, WANG Yali, MA Xiulong, REN Hongtao, BAO Xing. Analysis of the relationship between miR-429 and miR-200C expression and prognosis in patients with nasopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(3): 81-86.
[5] WANG Yingying, ZHOU Han, DONG Weida, XING Guangqian, CHEN Zhibin, ZHANG Qingzhao, ZHANG Liqing. Analysis of distant metastasis and prognosis of adenoid cystic carcinoma of the external auditory canal [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 1-6.
[6] TAN Yufang, YI Tianhua. Clinical characteristics and prognosis of sudden sensorineural hearing loss in post-irradiated nasopharyngeal carcinoma survivors: a report of 18 cases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 35-39.
[7] LIN Yushan, LU Biaoqing. Treatment of sudden seafness by heart and spleen [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 6-11.
[8] . Expression of cyclin E2 in hypopharyngeal cancer and its clinical significance [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 132-137.
[9] Rhinogenic headache is caused by rhinosinusitis or abnormal nasal anatomy. Currently, there are clear classifications and pain grading standards to diagnose the same. Further, its mechanism of action is now understood to involve trigeminal nerve stimulation and sensory neuropeptide substance P. Functional endoscopic surgery(FESS)is prioritized as a treatment modality. During surgery, it is imperative to restore the normal anatomy of the nasal cavity. Several clinical studies have reported that FESS was significantly effective in treating rhinogenic headache, with an overall effective rate of 90% and cure rate of 78%. Additionally, one report indicates that postoperative endoscopic examination and dressing change can effectively reduce the occurrence of complications and ensure safety of the treatment.. Dynamic analysis of rhinogenic headacheZHOU Fangming1, XIE Yan2, LIU Yang2 Overview JIANG Luyun2〓Guidance 1. Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, China 2. Department of Otorhinolaryngology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, ChinaAbstract: [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 130-133.
[10] XU Jinjing, HU Jinghua, WU Yuanqing, DENG Yi, YU Weiwei. Applications of CO2 laser microsurgery on laryngeal precancerous lesions and early glottic laryngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(3): 129-133.
[11] CHEN Huijun, SONG Shenghua, DONG Weida, ZHOU Han. Prognostic role of preoperative fibrinogen levels in patients with laryngeal squamous cell carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(2): 110-114.
[12] Yujing DING,Lan LAN,Qiuju WANG,Fei JI,Fen XIONG,Linyi XIE,Haina DING,Yin XIA,Hui ZHAO. Analysis of clinical characteristics and prognosis of post traumatic hearing loss [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 9-14.
[13] ZONG Xiaofang, HU Guohua, ZHONG Shixun, LEI Yan, JIANG Lizhu, KANG Houyong. Analysis of the factors affecting the prognosis of low-frequency descending sudden hearing loss without vertigo [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 33-37.
[14] CHEN Xuesong, FU Weiwei, LIU Jiangtao. The prognostic value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in intensity modulated radiation therapy for nasopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 50-53.
[15] Yangfan LIU,Jian JIA,Baoluo WAN. A retrospective study on clinic manifestation and pathological of the larynx leukoplakia in 76 cases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(5): 162-165.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd