山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (4): 16-22.doi: 10.6040/j.issn.1673-3770.1.2020.053

• 眼缺血综合征多学科精准诊疗 专家笔谈 • 上一篇    下一篇

磁共振动脉自旋标记技术在缺血性疾病中的应用研究

周卓华李红阳, 黄映湘, 王艳玲   

  1. 周卓华 综述 李红阳, 黄映湘, 王艳玲 审校首都医科大学附属北京友谊医院 眼科, 北京 100050
  • 收稿日期:2020-05-29 出版日期:2020-07-20 发布日期:2020-08-28
  • 基金资助:
    国家自然科学基金资助(81870686);首都卫生发展科研专项资助(首发2018-1-2021)

The application of arterial spin labeling in ischemic diseasesZHOU Zhuohua Overview LI Hongyang, HUANG Yingxiang, WANG Yanling Guidance Department of Ophthalmology, Beijing Friendship Hospital affiliated to Capital Medical University, Beijing 100050, ChinaAbstract:

Arterial spin labeling(ASL)is a non-invasive imaging technique that permits the quantitative analysis of tissue perfusion without contrast agents, and it has been widely used in ischemic disease research. This paper introduces the application of ASL in the assessment of ischemic ophthalmopathy and encephalopathy and compares it with other common examination techniques of the eye and brain. ASL can be used to monitor changes in cerebral blood flow and predict ischemic events, and it has been widely used in the study of ischemic encephalopathy. It can directly reflect the dynamics of blood flow through the chorioretinal vasculature, and it can be used as a reliable method for quantifying ocular blood perfusion. ASL is also relevant for the pathophysiological studies of chorioretinal diseases, which may contribute to the early diagnosis of ischemic ophthalmopathies. Currently, the application of ASL in ophthalmology is still limited, and further studies are needed to establish the utility of ASL in assessing ischemic ophthalmopathy.   

  1. Key words: Ischemic ophthalmopathy;
    Arterial spin labeling;
    Ischemic encephalopathy;
    Diagnosis;
    Magnetic resonance imaging缺血性疾病(如缺血性眼病、缺血性脑病)具有高发病率的特点, 且部分早期症状不典型, 早期发现、早期诊断可使患者得到及时治疗, 对于降低致残率和死亡率具有重要意义。随着影像学技术的发展, 该类疾病的检查手段多种多样, 磁共振动脉自旋标记(arterial spin labeling, ASL)技术作为一项新的成像技术应用于缺血性疾病的早期诊断, 在有些方面已经取得了可见的成效。现就ASL在缺血性疾病中的临床应用进行综述。
  • Received:2020-05-29 Online:2020-07-20 Published:2020-08-28

PDF (PC)

347

摘要： 磁共振动脉自旋标记技术(ASL)是一种非侵入性的影像学技术, 无需造影剂即可定量分析组织的血流灌注情况, 可重复性高, 对血流动力学相关指标敏感。本文主要介绍ASL在缺血性眼病及脑病中的应用, 并与眼部、脑部其他常用的血管造影等检查进行比较。ASL能够对脑部血流状态变化进行监测, 可预测脑部缺血性事件的发生, 目前已广泛应用于缺血性脑病的研究。研究表明ASL能够直接反映脉络膜视网膜组织的供血状况, 可作为定量眼部血流灌注的可靠方法, 同时对脉络膜视网膜疾病的病理生理研究具有一定意义, 可对缺血性眼病进行早期诊断。目前ASL在眼部的应用尚少, 尚需进一步研究以明确ASL在缺血性眼病中的效用。

关键词: 缺血性眼病, 磁共振动脉自旋标记, 缺血性脑病, 诊断, 磁共振成像

Abstract: Arterial spin labeling(ASL)is a non-invasive imaging technique that permits the quantitative analysis of tissue perfusion without contrast agents, and it has been widely used in ischemic disease research. This paper introduces the application of ASL in the assessment of ischemic ophthalmopathy and encephalopathy and compares it with other common examination techniques of the eye and brain. ASL can be used to monitor changes in cerebral blood flow and predict ischemic events, and it has been widely used in the study of ischemic encephalopathy. It can directly reflect the dynamics of blood flow through the chorioretinal vasculature, and it can be used as a reliable method for quantifying ocular blood perfusion. ASL is also relevant for the pathophysiological studies of chorioretinal diseases, which may contribute to the early diagnosis of ischemic ophthalmopathies. Currently, the application of ASL in ophthalmology is still limited, and further studies are needed to establish the utility of ASL in assessing ischemic ophthalmopathy.

Key words: Ischemic ophthalmopathy, Arterial spin labeling, Ischemic encephalopathy, Diagnosis, Magnetic resonance imaging

中图分类号: 

  • R77
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