山东大学耳鼻喉眼学报 ›› 2019, Vol. 33 ›› Issue (2): 35-38.doi: 10.6040/j.issn.1673-3770.0.2019.074

• 研究进展 • 上一篇    下一篇

复发鼻咽癌挽救性手术方法研究进展

徐文瑞,姜彦*()   

  1. 青岛大学附属医院耳鼻咽喉头颈外科、鼻颅底外科,山东省耳鼻咽喉头颈外科重点实验室,山东省数字医学与计算机辅助手术重点实验室,山东省高等学校数字医学临床诊疗与营养健康协同创新中心, 山东 青岛 266003
  • 收稿日期:2019-02-20 出版日期:2019-03-20 发布日期:2019-03-28
  • 通讯作者: 姜彦 E-mail:jiangyanoto@163.com

Surgery Treatment for Recurrent Nasopharyngeal Carcinoma

Wenrui XU,Yan JIANG*()   

  1. Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Hospital of Qingdao University, Shandong Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Shandong Key Laboratory of Digital Medicine and Computer Assisted Surgery, Shandong College Collaborative Innovation Center of Digital Medicine in Clinical Treatment and Nutrition Health, Qingdao 266003, Shandong, China
  • Received:2019-02-20 Online:2019-03-20 Published:2019-03-28
  • Contact: Yan JIANG E-mail:jiangyanoto@163.com

摘要:

鼻咽癌是我国常见的恶性肿瘤之一,尽管三维适形放疗、调强放疗、同步放化疗等治疗手段使鼻咽癌的局部控制率及总体生存率得到显著提高,仍有约10%的鼻咽癌在经过正规根治性治疗后发生局部或(和)区域复发。目前,复发鼻咽癌多采用再程放疗和手术治疗,对复发鼻咽癌常用的手术治疗方式进行综述。

关键词: 鼻咽肿瘤, 复发, 外科手术

Abstract:

Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in China. Although three-dimensional conformal radiotherapy, intensity-modulated radiotherapy, concurrent radiotherapy, and chemotherapy have significantly improved the local control rate and overall survival rate of NPC, about 10% of NPC recur locally and / or regionally after radical treatment. Recurrent nasopharyngeal carcinoma (NPC) is usually treated by re-operative radiotherapy and surgery. The choice of treatment method remains difficult. This article reviews the common surgical treatment methods and research progress of recurrent nasopharyngeal carcinoma.

Key words: Nasopharyngeal neoplasms, Recurrence, Surgical procedures, operative

中图分类号: 

  • R739.6
1 卢泰祥, 韩非, 李嘉欣. 复发鼻咽癌临床研究进展[J]. 中国癌症杂志, 2008, 18 (9): 661- 666.
doi: 10.3969/j.issn.1007-3639.2008.09.006
LU Taixiang , HAN Fei , LI Jiaxin . Advance in the clinical research On local recurrent nasopharyngeal carcinoma[J]. China Oncology, 2008, 18 (9): 661- 666.
doi: 10.3969/j.issn.1007-3639.2008.09.006
2 李金高, 陈晓钟, 林少俊, 等. 鼻咽癌复发、转移诊断专家共识[J]. 中华放射肿瘤学杂志, 2008, 27 (1): 7- 15.
doi: 10.3321/j.issn:1004-4221.2008.01.003
3 Fisch U , Pillsbury HC . Infratemporal fossa approach to lesions in the temporal bone and base of the skull[J]. Arch Otolaryngol, 1979, 105 (2): 99- 107.
doi: 10.1001/archotol.1979.00790140045008
4 Fisch U . Speech by honored guest. the infratemporal fossa approach for nasopharyngeal tumors[J]. The Laryngoscope, 1983, 93 (1): 36- 44.
doi: 10.1288/00005537-198301000-00007
5 Choi JY , Lee WS . Curative surgery for recurrent nasopharyngeal carcinoma via the infratemporal fossa approach[J]. Arch Otolaryngol Head Neck Surg, 2005, 131 (3): 213- 216.
doi: 10.1001/archotol.131.3.213
6 Tu GY , Hu YH , Xu GZ , et al. Salvage surgery for nasopharyngeal carcinoma[J]. Arch Otolaryngol Head Neck Surg, 1988, 114 (3): 328- 329.
doi: 10.1001/archotol.1988.01860150110026
7 Fee WE Jr , Gilmer PA , Goffinet DR . Surgical management of recurrent nasopharyngeal carcinoma after radiation failure at the primary site[J]. Laryngoscope, 1988, 98 (11): 1220- 1226.
doi: 10.1288/00005537-198811000-00013
8 伍国号, 黄晓明, 陈福进, 等. 头颈肿瘤外科手术术式与技巧[M]. 北京: 人民军医出版社, 2004: 42- 43.
9 Wei WI . Cancer of the nasopharynx: functional surgical salvage[J]. World J Surg, 2003, 27 (7): 844- 848.
doi: 10.1007/s00268-003-7110-9
10 Wei WI , Lam KH , Sham JS . New approach to the nasopharynx: the maxillary swing approach[J]. Head Neck, 1991, 13 (3): 200- 207.
doi: 10.1002/(ISSN)1097-0347
11 孙彦, 肖红俊, 韦霖. 上颌骨翻转径路在鼻咽癌挽救手术中的应用[J]. 山东大学耳鼻喉眼学报, 2006, 20 (2): 102- 104, 113.
doi: 10.3969/j.issn.1673-3770.2006.02.002
12 Wei WI , Chan JYW , Ng RWM , et al. Surgical salvage of persistent or recurrent nasopharyngeal carcinoma with maxillary swing approach-Critical appraisal after 2 decades[J]. Head Neck, 2011, 33 (7): 969- 975.
doi: 10.1002/hed.21558
13 Chan JY , Tsang RK , Wei WI . Morbidities after maxillary swing nasopharyngectomy for recurrent nasopharyngeal carcinoma[J]. Head Neck, 2015, 37 (4): 487- 492.
doi: 10.1002/hed.23633
14 Yumoto E , Okamura H , Yanagihara N . Transmandibular transpterygoid approach to the nasopharynx, parapharyngeal space, and skull base[J]. Ann Otol Rhinol Laryngol, 1992, 101 (5): 383- 389.
doi: 10.1177/000348949210100502
15 Yoshizaki T , Wakisaka N , Murono S , et al. Endoscopic nasopharyngectomy for patients with recurrent nasopharyngeal carcinoma at the primary site[J]. Laryngoscope, 2005, 115 (8): 1517- 1519.
doi: 10.1097/01.MLG.0000165383.35100.17
16 Chen MK , Lai JC , Chang CC , et al. Minimally invasive endoscopic nasopharyngectomy in the treatment of recurrent T1-2a nasopharyngeal carcinoma[J]. Laryngoscope, 2007, 117 (5): 894- 896.
doi: 10.1097/MLG.0b013e3180381644
17 Al-Sheibani S , Zanation AM , Carrau RL , et al. Endoscopic endonasal transpterygoid nasopharyngectomy[J]. Laryngoscope, 2011, 121 (10): 2081- 2089.
doi: 10.1002/lary.22165
18 Liu J , Yu HP , Sun XC , et al. Salvage endoscopic nasopharyngectomy for local recurrent or residual nasopharyngeal carcinoma: a 10-year experience[J]. Int J Clin Oncol, 2017, 22 (5): 834- 842.
doi: 10.1007/s10147-017-1143-9
19 Wong EHC , Liew YT , Abu Bakar MZ , et al. A preliminary report on the role of endoscopic endonasal nasopharyngectomy in recurrent rT3 and rT4 nasopharyngeal carcinoma[J]. Eur Arch Otorhinolaryngol, 2017, 274 (1): 275- 281.
doi: 10.1007/s00405-016-4248-2
20 You R , Zou X , Hua YJ , et al. Salvage endoscopic nasopharyngectomy is superior to intensity-modulated radiation therapy for local recurrence of selected T1-T3 nasopharyngeal carcinoma-A case-matched comparison[J]. Radiother Oncol, 2015, 115 (3): 399- 406.
doi: 10.1016/j.radonc.2015.04.024
21 Lam WKJ , Chan JYK . Recent advances in the management of nasopharyngeal carcinoma[J]. F1000Res, 2018, 7: 1829.
doi: 10.12688/f1000research.15066.1
22 Tsang RK , To VS , Ho AC , et al. Early results of robotic assisted nasopharyngectomy for recurrent nasopharyngeal carcinoma[J]. Head Neck, 2015, 37 (6): 788- 793.
doi: 10.1002/hed.23672
23 Tsang RK , Wei WI . Salvage surgery for nasopharyngeal cancer[J]. World J Otorhinolaryngol Head Neck Surg, 2015, 1 (1): 34- 43.
doi: 10.1016/j.wjorl.2015.09.006
24 Wei WI , Kwong DL . Recurrent nasopharyngeal carcinoma: surgical salvage vs. additional chemoradiation[J]. Curr Opin Otolaryngol Head Neck Surg, 2011, 19 (2): 82- 86.
doi: 10.1097/MOO.0b013e328344a599
[1] 姜彦. 鼻咽癌复发及鼻内镜外科手术的应用[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 1-11.
[2] 陈冬平,杨致欢,张炎,方楠,齐斌. 复发鼻咽癌手术治疗地位的思考[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 12-16.
[3] 邱前辉,陈卓. 鼻内镜手术治疗首诊局部晚期鼻咽癌及放疗后严重并发症的作用[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 17-20.
[4] 王振霖,刘俊其. 鼻咽癌外科治疗中的颈内动脉保护[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 21-25.
[5] 陆海军,刘霁,丁晓. 鼻咽癌的综合治疗研究进展[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 26-30.
[6] 陈瑞,李杰恩. 鼻咽癌放疗后诱发头颈部恶性肿瘤的治疗[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 31-34.
[7] 刘全,孙希才,于华鹏,赵可庆,张焕康,赵卫东,顾瑜蓉,李厚勇,王德辉,余洪猛. 鼻内镜下鼻咽癌切除术的手术分型[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 39-45.
[8] 高俊潇,邱前辉. 黏膜瓣在鼻咽癌放疗后鼻内镜手术修复颅底组织缺损中的应用[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 46-50.
[9] 赵丽娟,姜彦,于龙刚,蔡亮,陈敏,张继生,李志远,鞠建宝,李娜. 鼻咽癌内镜手术治疗临床分析[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 51-56.
[10] 孙笑晗,李娜. 西班牙医学肿瘤学会鼻咽癌临床指南(2017)介绍[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 57-59.
[11] 王俊,邢奋丽,朱萍,孙亚萍,汤翠菊. 鼻咽癌放疗期间两种鼻腔冲洗方法的应用效果比较[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 60-63.
[12] 王玥,刘芊,王海波. 自发性脑脊液耳漏的研究进展[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 130-135.
[13] 余洪猛,刘琢扶,戴琪. 合并哮喘的慢性鼻-鼻窦炎的鼻内镜手术治疗[J]. 山东大学耳鼻喉眼学报, 2019, 33(1): 38-41.
[14] 齐岩,刘俊其,彭舒娅,罗凯,张名霞,王振霖. 鼻内镜下选择性翼管神经切断术对伴有变应性鼻炎的慢性鼻窦炎的疗效观察[J]. 山东大学耳鼻喉眼学报, 2019, 33(1): 109-113.
[15] 雷文斌,刘其洪. CO2激光手术治疗复发性呼吸道乳头状瘤[J]. 山东大学耳鼻喉眼学报, 2018, 32(6): 8-12.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] 林彬,王挥戈 . 功能性内镜鼻窦手术后鼻黏膜纤毛转归的研究[J]. 山东大学耳鼻喉眼学报, 2006, 20(6): 481 -487 .
[2] 曹忠良 . 颌面复合伤155例临床分析[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 89 -89 .
[3] 栾建刚,梁传余,文艳君,李炯 . 抑制表皮生长因子受体基因表达的pSIREN-ShuttleRNAi表达载体的构建[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 4 -8 .
[4] 毕景云 . 鼻中隔矫正术后血肿的处理[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 90 -91 .
[5] 楼正才 . 掌拳击伤鼓膜损伤机制及临床特点分析[J]. 山东大学耳鼻喉眼学报, 2008, 22(2): 188 -188 .
[6] 孟庆国,卢永田,范献良 . 杀伤细胞免疫球蛋白样受体基因多态性与鼻咽癌的关联性[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 196 -199 .
[7] 谢治年 综述,姬长友 审校 . RNA干扰及其在喉鳞癌研究中的应用[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 200 -203 .
[8] 刘强和,罗香林,耿宛平,陈 晨,雷 迅,刘芳贤,邓 明 . 快速老化小鼠的听功能和耳蜗螺旋神经元的增龄性变化[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 215 -217 .
[9] 杨淑娟,袁 英,刘付星,秦海平 . 美宝湿润烧伤膏联合蛋膜贴补治疗外伤性鼓膜穿孔40例[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 227 -227 .
[10] 林峰,梁勇,卢永田,万丽霞 . 鼻内翻性乳头状瘤临床分型和术式选择[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 231 -233 .