头颈部转移性透明细胞癌5例并文献复习

doi:10.6040/j.issn.1673-3770.0.2020.481

摘要/Abstract

摘要： 目的探讨泌尿系统透明细胞癌转移至头颈的部位和治疗方法。方法总结我院2011年至2018年收治的具有完整临床资料的5例头颈部转移性透明细胞癌,分析原发疾病、原发病治疗方法、转移时间、转移部位、转移灶治疗方法、预后等临床资料。结果 5例透明细胞癌原发灶位于肾脏4例、膀胱1例,原发灶均行根治性手术。转移时间为原发灶术后1~10年,转移至上颌窦1例、额窦额骨1例、额窦筛窦1例、室带1例、额部皮下1例。4例转移灶手术后均复发并死于全身转移,仅1例皮下转移患者存活。结论透明细胞癌转移至头颈部较为罕见,根治性手术切除是治疗头颈部转移性透明细胞癌的主要方法,患者多死于全身多发转移。

关键词: 头颈部, 透明细胞癌, 转移, 治疗, 预后

Abstract: Objective To explore the location and treatment of the metastasis of clear cell carcinoma of the urinary system to the head and neck. Methods Five cases of metastatic clear cell carcinoma of the head and neck admitted to our hospital during 2011-2018 were summarized. The clinical data and treatment method of the primary disease, time of metastasis, site of metastasis, treatment approach for the metastasis, and prognosis were recorded. Results Five cases of clear cell carcinoma involved primary lesions in the kidney(4 cases)and bladder(1 case), all of which underwent radical surgery. The metastases developed 1-10 years after the surgery of the primary lesions, including 1 case involving the maxillary sinus, 1 case involving the frontal sinus and bone, 1 case involving the frontal and ethmoid sinus, 1 case involving the ventricular band, and 1 case involving the frontal subcutaneous area. All four patients had recurrence and died of systemic metastasis, and only 1 patient with subcutaneous metastasis survived. Conclusion Metastasis of clear cell carcinoma to the head and neck is rare. Radical surgical resection is the main method for treating metastatic clear cell carcinoma of the head and neck. Most patients die due to multiple metastases throughout the body.

Key words: Head and neck, Clear cell carcinoma, Metastasis, Treatment, Prognosis

中图分类号:

R739.62

刘盼,王川,赵泽祺,吴梅,徐继峰,李巍,张伟强,刘稳. 头颈部转移性透明细胞癌5例并文献复习[J]. 山东大学耳鼻喉眼学报, 2021, 35(4): 45-50.

LIU Pan, WANG Chuan, ZHAO Zeqi, WU Mei, XU Jifeng, LI Wei, ZHANG Weiqiang, LIU Wen. Five cases of metastatic clear cell carcinoma of the head and neck: a case report and literature review[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(4): 45-50.

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