microRNA在过敏性鼻炎发病机制中的研究进展

doi:10.6040/j.issn.1673-3770.0.2020.365

摘要/Abstract

摘要： 过敏性鼻炎是临床常见病,发病机制相对复杂,目前在诊断和治疗方面仍有缺陷。miRNA是近年来研究的热点,其在过敏性鼻炎中的研究让我们对疾病有了新的认识。文章主要从固有免疫、适应性免疫及表观遗传学因素等角度总结miRNA与过敏性鼻炎的关系,以期揭示过敏性鼻炎的发病机制。

关键词: microRNA, 过敏性鼻炎, 发病机制, 固有免疫, 适应性免疫, 表观遗传学

Abstract: The pathogenesis of allergic rhinitis, a common clinical disease, is relatively complex, and there are still defects in its diagnosis and treatment. The microRNA has been a research hotspot in recent years, and studies on allergic rhinitis provided a new understanding of the disease. This study summarizes the relationship between microRNA and allergic rhinitis in the perspectives of innate immunity, adaptive immunity, and epigenetic factors, in order to determine its pathogenesis.

Key words: MicroRNA, Allergic rhinitis, Pathogenesis, Innate immunity, Adaptive immunity, Epigenetic

中图分类号:

R765.22

王宇婷，王嘉玺. microRNA在过敏性鼻炎发病机制中的研究进展[J]. 山东大学耳鼻喉眼学报, 2021, 35(5): 98-104.

WANG Yuting，,WANG Jiaxi. Research developments on microRNA in the pathogenesis of allergic rhinitis[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(5): 98-104.

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