Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (3): 281-289.doi: 10.6040/j.issn.1673-3770.0.2020.519

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Meta-analysis of the curative effect of traditional Chinese medicine decoction combined with conventional western medicine on allergic rhinitis

ZHU Zhengru1, ZHANG Xiaobing2   

  1. 1. Department of Otorhinolaryngology & Head and Neck Surgery, Xijing Hospital, Xi'an 710000, Shaanxi, China;
    2. Department of Otorhinolaryngology & Head and Neck Surgery, the First Hospital of Lanzhou University, Lanzhou 730000, Gansu, China
  • Published:2022-06-15

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Abstract: Objective Meta-analysis was conducted to explore the influence of combined Chines decoctione and conventional western medicine on the short-term and long-term efficacy of allergic rhinitis. Methods Computer retrieval Chinese National Knowledge Infrastructure(CNKI), Wan Fang Data, VIP, CBM, Pubmed, Embase, The Cochrane Library databases of combining traditional Chinese and western medicine treatment of allergic rhinitis in clinical research of randomized controlled trials, from building Library retrieval timeuntil October 2020. After quality evaluation and relevant data extraction by two professional researchers, RevMan5.3 software and Stata 15.0 software were used for Meta analysis. Results In the end into the 20 research, a total of 2056 patients, using fixed effect model to the total effect value to merge, Meta analysis results show that the recent effective rate of combining traditional Chinese decoctione and conventional western medicine treatment of allergic rhinitis was superior to that of control group ［RR=1.18, 95%CI(1.13,1.22), P<0.001］, long-term effectiveness significantly better than control group ［RR=1.79, 95%CI(1.50,2.13), P<0.001］, After classification, the short-term effective rates of tonifying fei-qi method, fortifying the Spleen and boosting qi method and Qingxuan-fei-qi method combined with conventional western medicine were all better than those of the control group. Meta-analysis results were ［RR=1.17, 95%CI(1.11,1.23), P<0.001］,［RR=1.18, 95%CI(1.09,1.29), P<0.001］,［RR=1.18, 95%CI(1.10,1.26), P<0.001］, respectively. the difference is statistically significant. In this study, funnel plot showed the basic symmetry between the left and the right, and the begg bias test was used to obtain P=0.069>0.05 means that the publication bias of the 19 literatures selected in this study is small. Conclusion This study shows that the combined treatment of Chinese medicine decoction and conventional western medicine for AR is superior to the treatment of western medicine alone in both short-term and long-term efficacy.

Key words: integrated traditional Chinese and western medicine, Allergic rhinitis, Randomized controlled trial, Meta analysis

CLC Number: 

  • R765
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