关键词: 颅骨骨折, 基底, 脑脊液鼻漏, 外科手术

Abstract: Objective： To study the incidence rate, position and time of cerebrospinal fluid(CSF) leak after traumatic skull base and explore a more effective treatment. Method： The clinical data of 358 patients with traumatic skull base fracture were retrospectively analyzed. Results： CSF leak was found in 88 cases(24.6%), 56 of whom resulted from anterior cranial fossa, 23 from cranial fossa media, and 9 from anteriormiddle cranial fossa. About 64.8% of the CSF leak (57 cases) occurred in 48 hours after fracture, and the latest was found 28 years after fracture. CSF leak was cured by conservative treatment in 73 patients, by once operation in 11, and by twice operations in 3. One patient died of breathing and circulating exhaustion induced by the infection of intracranial part after three times surgeries. Among participants with surgery, 4 was successfully repaired by endoscopy. Conclusion： The response rate of CSF leak seems to have a relationship with the position and duration of fracture . Nasendoscopy has salutary effect on CSF leak for its less sideeffect and exact operation.

Key words: basilar, Cerebrospinal fluid rhinorrhea, Skull fracture, Surgical procedures, operative