山东大学耳鼻喉眼学报 ›› 2016, Vol. 30 ›› Issue (6): 22-23.doi: 10.6040/j.issn.1673-3770.0.2016.178

• 论著 • 上一篇    下一篇

碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎35例

沈莉   

  1. 溧阳市中医医院耳鼻喉科, 江苏 溧阳 213300
  • 收稿日期:2016-04-21 出版日期:2016-12-16 发布日期:2016-12-16
  • 作者简介:沈莉. E-mail:shenli_pig@sohu.com

Efficacy of sodium bicarbonate and fluconazole in the treatment of fungal otitis externa.

SHEN Li   

  1. Department of Otolaryngology, Liyang Traditional Chinese Medicine Hospital, Liyang 213300, Jiangsu, China
  • Received:2016-04-21 Online:2016-12-16 Published:2016-12-16

摘要: 目的 探讨碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎的疗效。 方法 使用随机平行对照方法,将真菌性外耳道炎患者105例,分为治疗组(碳酸氢钠联合氟康唑注射液耳浴);对照一组(氟康唑注射液耳浴);对照二组(2%水杨酸酒精耳浴),每组35例,连用10 d为一疗程,随访一年观察疗效。 结果 3个组的总有效率分别为91.43%、85.71%、77.14%,治疗组疗效优于2个对照组(P<0.05)。 结论 碳酸氢钠联合氟康唑注射液治疗真菌性外耳道炎的疗效优于单独采用氟康唑注射液或2%水杨酸酒精。

关键词: 碳酸氢钠, 氟康唑, 水杨酸, 真菌性外耳道炎

Abstract: Objective To explore the clinical efficacy of sodium bicarbonate combined with fluconazole in the treatment of fungal otitis externa. Methods Using random parallel control method, 105 patients with fungal otitis externa were divided into three groups: the treatment group(ear bath with sodium bicarbonate plus fluconazole injection); control group 1(ear bath with fluconazole injection); control group 2(ear bath with 2% salicylic acid alcohol), with 35 cases in each group. The treatment lasted for 10 days. The patients were followed up for one year to observe the curative effect. Results The total effective rate of the 3 groups were 91.43%, 85.71%, and 77.14%. The efficacy of the treatment group was better than that of the control groups(P<0.05). Conclusion Sodium bicarbonate combined with fluconazole is better than 2% salicylic acid alcohol or fluconazole alone in the treatment of fungal otitis externa.

Key words: Fluconazole, Salicylic acid, Sodium bicarbonate, Fungal otitis externa

中图分类号: 

  • R763
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