山东大学耳鼻喉眼学报 ›› 2019, Vol. 33 ›› Issue (1): 28-32.doi: 10.6040/j.issn.1673-3770.1.2018.037

• 专家笔谈 • 上一篇    下一篇

我国儿童哮喘患病与诊治现状

刘传合*()   

  1. 首都儿科研究所附属儿童医院变态反应科，北京 100020
  • 收稿日期:2018-11-08 出版日期:2019-01-20 发布日期:2019-01-28
  • 通讯作者: 刘传合 E-mail:liuchcip@126.com
  • 作者简介:刘传合，首都儿科研究所附属儿童医院变态反应科主任兼哮喘防治中心与肺功能室主任，研究员，主任医师，硕士生导师。主要学术任职：中华医学会变态反应学分会特异性诊断与免疫治疗学组副组长，中华医学会呼吸病学分会呼吸治疗与肺功能学组委员，中华医学会儿科学分会呼吸学组秘书，中国医师协会变态反应医师分会委员，中国医师协会儿科医师分会变态反应专委会副主任委员，全国儿童哮喘防治协作组、肺功能协作组副组长。《中华儿科杂志》《临床儿科杂志》《中华临床免疫与变态反应杂志》编委。主要研究方向：儿童过敏性疾病、呼吸系统疾病的临床与基础研究工作。主持和参与了《全球哮喘防治创议》《过敏性鼻炎的处理及其对哮喘的影响》的翻译工作，参与制定了我国《儿童哮喘防治指南》等。承担了北京市自然科学基金、教育部留学归国基金、首都发展基金联合攻关项目、卫生部公益性行业科研专项项目，发表论文70余篇，主编参编书籍5部

The prevalence, diagnosis and management of asthma in children in China

Chuanhe LIU*()   

  1. Department of Allergy, Children′s Hospital of Capital Institute of Pediatrics, Beijing 100020, China
  • Received:2018-11-08 Online:2019-01-20 Published:2019-01-28
  • Contact: Chuanhe LIU E-mail:liuchcip@126.com

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摘要：

近20余年，我国儿童哮喘患病率不断升高，不同地区及城市间差异较大。儿童哮喘因发作看急诊比例以及住院率仍然很高，其早期确诊率则较低，长期控制用药和管理亦不理想。儿科医生临床实践中应充分理解和正确应用指南，合理利用辅助检查手段，从而提高哮喘确诊率，早期给予哮喘患儿恰当的治疗方案和个体化预防措施，方可全面提高哮喘防治水平，从而改善预后。

关键词: 儿童, 哮喘, 患病率, 诊断, 治疗, 预后

Abstract:

In the past 20 years, the prevalence of childhood asthma has been increasing in China; its prevalence differs greatly between urban and rural populations. The proportion of asthma attack-related emergency room visits and hospitalization in children is still very high; the early diagnosis rate of childhood asthma is low and related treatment and management is not ideal. With complete understanding of the guidelines, correct applications in clinical practice, and appropriate laboratory examinations, pediatricians can improve early diagnosis of asthma and provide appropriate treatment plans and individualized preventive suggestions to children with asthma at an early stage; this can comprehensively improve asthma prevention and control and therefore, improve its prognosis.

Key words: Children, Asthma, Prevalence, Diagnosis, Treatment, Prognosis

中图分类号: 

  • R562.2
1 全国儿科哮喘协作组, 中国疾病预防控制中心环境与健康相关产品安全所. 第三次中国城市儿童哮喘流行病学调查[J]. 中华儿科杂志, 2013, 51 (10): 729- 735.
doi: 10.3760/cma.j.issn.0578-1310.2013.10.003
The National Cooperative Group on Childhood Asthma , Institute of Environmental Health and Related Prod . Third nationwide survey of childhood asthma in urban areas of China[J]. Chinese Journal of Pediatrics, 2013, 51 (10): 729- 735.
doi: 10.3760/cma.j.issn.0578-1310.2013.10.003
2 刘传合, 洪建国, 尚云晓, 等. 中国16城市儿童哮喘患病率20年对比研究[J]. 中国实用儿科杂志, 2015, 30 (8): 596- 600.
LIU Chuanhe , HONG Jianguo , SHANG Yunxiao , et al. Comparison of asthma prevalence in children from 16 cities of China in 20 years[J]. Chinese Journal of Practical Pediatrics, 2015, 30 (8): 596- 600.
3 金克.新疆乌鲁木齐市儿童哮喘患病情况调查及危险因素分析[D].乌鲁木齐:新疆医科大学, 2012.
4 童蕾, 李云, 钟礼立, 等. 长沙市儿童哮喘危险因素调查分析[J]. 湖南师范大学学报(医学版), 2014, 11 (1): 19- 23.
TONG Lei , LI Yun , ZHONG Lili , et al. The asthma risk factors analysis of Changsha childhood[J]. Journal of Hunan Normal University(Medical Science), 2014, 11 (1): 19- 23.
5 Zhu WJ , Ma HX , Cui HY , et al. Prevalence and treatment of children's asthma in rural areas compared with urban areas in Beijing[J]. Chin Med J, 2015, 128 (17): 2273- 2277.
doi: 10.4103/0366-6999.163381
6 刘艳琳, 唐素萍, 王世彪, 等. 2010年福建省福州城乡0~14岁儿童哮喘流行病学调查[J]. 中国妇幼健康研究, 2015, 26 (2): 184- 187, 188.
doi: 10.3969/j.issn.1673-5293.2015.02.006
LIU Yanlin , TANG Suping , WANG Shibiao , et al. Prevalence survey of asthma in 0-14 year old children in 2010 in urban and rural areas in Fuzhou of Fujian Province[J]. Chinese Journal of Woman and Child Health Research, 2015, 26 (2): 184- 187, 188.
doi: 10.3969/j.issn.1673-5293.2015.02.006
7 郑明平, 王晶晶, 唐素萍, 等. 1860例畲族儿童支气管哮喘流行病学调查分析[J]. 中国医药导报, 2014, 11 (11): 112- 114.
ZHENG Mingping , WANG Jingjing , TANG Suping , et al. Epidemiological survey of bronchial asthma in 1860 children of She ethnic minority[J]. China Medical Herald, 2014, 11 (11): 112- 114.
8 喻昌利, 王袁, 李雪梅, 等. 唐山地区中小学生支气管哮喘的流行病学调查[J]. 实用预防医学, 2014, 21 (12): 1451- 1453.
doi: 10.3969/j.issn.1006-3110.2014.012.013
9 蒙文娟.贵阳地区193例儿童哮喘患病情况调查及相关因素分析[D].贵阳:贵阳医学院, 2013.
10 邵明军, 刘传合, 王强, 等. 北京市城区哮喘儿童过敏状况及危险因素调查[J]. 中国医刊, 2014, 49 (7): 48- 51.
doi: 10.3969/j.issn.1008-1070.2014.07.016
SHAO Mingjun , LIU Chuanhe , WANG Qiang , et al. Investigation of allergic status and risk factors affecting the incidence of asthma in children from Beijing urban area[J]. Chinese Journal of Medicine, 2014, 49 (7): 48- 51.
doi: 10.3969/j.issn.1008-1070.2014.07.016
11 Platts-Mills TA , Rakes G , Heymann PW . The relevance of allergen exposure to the development of asthma in childhood[J]. J Allergy Clin Immunol, 2000, 105 (2 Pt 2): S503- S508.
12 沙莉, 邵明军, 卢旭, 等. 北京城区与农村儿童支气管哮喘过敏特征及诱发因素的对比研究[J]. 中华实用儿科临床杂志, 2017, 32 (9): 702- 704.
doi: 10.3760/cma.j.issn.2095-428X.2017.09.016
SHA Li , SHAO Mingjun , LU Xu , et al. Comparative study on the allergic characteristics and trigger factors of rural and urban children asthma in Beijing[J]. Journal of Applied Clinical Pediatrics, 2017, 32 (9): 702- 704.
doi: 10.3760/cma.j.issn.2095-428X.2017.09.016
13 沙莉, 刘传合, 邵明军, 等. 中国城市儿童哮喘诊治状况十年对比[J]. 中华儿科杂志, 2016, 54 (3): 182- 186.
doi: 10.3760/cma.j.issn.0578-1310.2016.03.005
SHA Li , LIU Chuanhe , SHAO Mingjun , et al. Ten years comparison of diagnosis and treatment of asthma in urban children in China[J]. Chinese Journal of Pediatrics, 2016, 54 (3): 182- 186.
doi: 10.3760/cma.j.issn.0578-1310.2016.03.005
14 Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary[J]. Eur Respir J. 2018, 51(2). pii:0751387. doi:10.1183/13993003.51387-2007.
15 中华医学会儿科学会呼吸学组, 《中华儿科杂志》编辑委员会. 儿童支气管哮喘诊断与防治指南[J]. 中华儿科杂志, 2008, 46 (10): 745- 753.
doi: 10.3321/j.issn:0578-1310.2008.10.006
THE Subspecialty Group of Respiratory Diseases, the Society of Pediatrics , Chinese Medical Association, The Editorial Board, Chinese Journal of Pediatrtics. . Guideline for the diagnosis and optimal management of asthma in children[J]. Chinese Journal of Pediatrics, 2008, 46 (10): 745- 753.
doi: 10.3321/j.issn:0578-1310.2008.10.006
16 中华医学会儿科学分会呼吸学组慢性咳嗽协作组, 《中华儿科杂志》编辑委员会. 中国儿童慢性咳嗽诊断与治疗指南(2013年修订)[J]. 中华儿科杂志, 2014, 52 (3): 184- 188.
doi: 10.3760/cma.j.issn.0578-1310.2014.03.005
17 王金荣, 李志鹏, 金亚, 等. 2010年至2011年济南城区儿童支气管哮喘患病情况分析[J]. 中华实用儿科临床杂志, 2013, 28 (10): 778- 780.
doi: 10.3760/cma.j.issn.2095-428X.2013.10.017
WANG Jinrong , LI Zhipeng , JIN Ya , et al. Epidemiological survey of childhood asthma in urban area of Jinan city between 2010 and 2011[J]. Journal of Applied Clinical Pediatrics, 2013, 28 (10): 778- 780.
doi: 10.3760/cma.j.issn.2095-428X.2013.10.017
18 王鑫, 张亚京, 宁立华, 等. 2000年与2010年包头城区儿童哮喘患病相关因素的调查比较[J]. 中华哮喘杂志(电子版), 2013, 7 (6): 394- 398.
WANG Xin , ZHANG Yajing , NING Lihua , et al. Comparative analysis in prevalence and risk factors of children's asthma in Baotou urban district[J]. Chinese Journal of Asthma(Electronic Version), 2013, 7 (6): 394- 398.
19 刘传合, 沙莉, 邵明军, 等. 北京市城区儿童支气管哮喘诊断与管理状况的调查[J]. 中华实用儿科临床杂志, 2013, 28 (16): 1212- 1215.
doi: 10.3760/cma.j.issn.2095-428X.2013.16.005
LIU Chuanhe , SHA Li , SHAO Mingjun , et al. Status of diagnosis and management of children with asthma in Beijing urban area[J]. Journal of Applied Clinical Pediatrics, 2013, 28 (16): 1212- 1215.
doi: 10.3760/cma.j.issn.2095-428X.2013.16.005
20 Xiang L , Zhao J , Zheng YJ , et al. Uncontrolled asthma and its risk factors in Chinese children: A cross-sectional observational study[J]. J Asthma, 2016, 53 (7): 699- 706.
doi: 10.3109/02770903.2016.1144199
21 Wong GW , Kwon N , Hong JG , et al. Pediatric asthma control in Asia: phase 2 of the Asthma Insights and Reality in Asia-Pacific (AIRIAP 2) survey[J]. Allergy, 2013, 68 (4): 524- 530.
doi: 10.1111/all.12117
22 杨哲, 宋欣, 李硕, 等. 支气管哮喘控制患儿小气道功能状况及影响因素分析[J]. 中华实用儿科临床杂志, 2017, 32 (16): 1244- 1247.
doi: 10.3760/cma.j.issn.2095-428X.2017.16.011
YANG Zhe , SONG Xin , LI Shuo , et al. The condition of small airway function and its related influence factors in controlled bronchial asthmatic children[J]. Journal of Applied Clinical Pediatrics, 2017, 32 (16): 1244- 1247.
doi: 10.3760/cma.j.issn.2095-428X.2017.16.011
23 田春雨, 沙莉, 刘传合, 等. 北京市城区哮喘患儿六年转归的随访研究[J]. 中华儿科杂志, 2018, 56 (3): 200- 205.
doi: 10.3760/cma.j.issn.0578-1310.2018.03.009
Tian Chunyu , Sha Li , Liu Chuanhe , et al. A follow-up study of six years' outcome of children with asthma in urban area of Beijing[J]. Chinese Journal of Pediatrics, 2018, 56 (3): 200- 205.
doi: 10.3760/cma.j.issn.0578-1310.2018.03.009
24 王慧敏, 朱雯靓, 刘传合, 等. 年幼儿童反复喘息发作的转归及不同表型的危险因素[J]. 临床儿科杂志, 2018, 36 (4): 272- 276.
doi: 10.3969/j.issn.1000-3606.2018.04.009
WANG Huimin , ZHU Wenjing , LIU Chuanhe , et al. The outcome of recurrent wheezing and the risk factors of its different phenotypes in young children[J]. Journal of Clinical Pediatrics, 2018, 36 (4): 272- 276.
doi: 10.3969/j.issn.1000-3606.2018.04.009
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