山东大学耳鼻喉眼学报 ›› 2022, Vol. 36 ›› Issue (3): 1-6.doi: 10.6040/j.issn.1673-3770.0.2022.184

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变态反应检测与诊断的临床应用及意义

程雷1,2,3,许秋艳2,4,陈浩5   

  1. 1.南京医科大学第一附属医院/江苏省人民医院 耳鼻咽喉科, 江苏 南京 210029;
    2.南京医科大学第一附属医院/江苏省人民医院 过敏诊疗中心, 江苏 南京 210029;
    3.南京医科大学国际变态反应研究中心, 江苏 南京 210029;
    4.南京医科大学附属苏州科技城医院 儿科, 江苏 苏州 215153;
    5.华中科技大学同济医学院附属同济医院 过敏反应科, 湖北 武汉 430030
  • 发布日期:2022-06-15
  • 通讯作者: 程雷. E-mail:chenglei@jsph.org.cn
  • 基金资助:
    江苏高校优势学科建设工程(JX10231801)

Clinical use and significance of allergy testing and diagnostics

CHENG Lei1,2,3, XU Qiuyan2,4, CHEN Hao5   

  1. 1. Department of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China;
    2. Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China;
    3. International Centre for Allergy Research, Nanjing Medical University, Nanjing 210029, Jiangsu, China;
    4. Department of Pediatrics, Suzhou Science & Technology Town Hospital, Nanjing Medical University, Suzhou 215153, Jiangsu, China;
    5.Department of Allergy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
  • Published:2022-06-15

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摘要： 变态反应疾病是当今全球最常见的疾病之一,而且疾病负担继续在增加。明确变应原致敏并识别引起变态反应疾病的变应原对于制定疾病管理策略至关重要。介绍目前国内外在诊断IgE介导的Ⅰ型变态反应中最常用的体内和体外检测方法及其临床意义。

关键词: 变应原, 免疫球蛋白E, 皮肤试验, 血清学检测, 诊断

Abstract: Allergic diseases are among the most prevalent diseases worldwide and their burden on healthcare systems continues to increase. Confirmation of allergen sensitization and the identification of causal allergens are essential for developing management strategies for these maladies. This paper provides an updated introduction of the most commonly used detection methods, both in vivo and in vitro, in the diagnosis of type I IgE-mediated allergy and its clinical significance.

Key words: Allergens, Immunoglobulin E, Skin tests, Serologic tests, Diagnosis

中图分类号: 

  • R392.8
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