揿针治疗变应性鼻炎临床疗效的Meta分析

doi:10.6040/j.issn.1673-3770.0.2022.364

Abstract

Abstract: Objective To systematically evaluate the clinical efficacy and safety of intradermal acupuncture in the treatment of allergic rhinitis using Meta-analysis. Methods PubMed, The Cochrane Library, Web of Science, SinoMed, VIP, CNKI, and Wanfang databases were searched for randomized controlled trials which used intradermal acupuncture to treat allergic rhinitis from database inception to October 1, 2022. Two researchers conducted independent screening, data extraction, bias risk assessment, and meta-analysis of the literature. Results This study included 29 clinical trials and 2342 patients. Compared with the positive control group, the intradermal acupuncture combined therapy group showed improvements in clinical total effective rate ［RR=1.24, 95%CI(1.16, 1.33), P<0.001］, quantitative scores of symptoms and signs ［MD=-0.67, 95%CI(-1.12, -0.22), P=0.003］, visual analogue score of nasal symptoms ［MD=-0.62, 95%CI(-0.97, -0.28), P<0.001］, number of recurrences ［RR=0.58, 95%CI(0.41, 0.82), P=0.002］, nasal resistance ［MD=-0.13, 95%CI(-0.21, -0.05), P=0.001］, and quality of life score for nasal conjunctivitis［MD=-4.17, 95%CI(-6.06, -2.29), P<0.001］. Compared with antihistamines, there was no significant difference in clinical total effective rate［RR=1.01, 95%CI(0.92, 1.11), P=0.78］ and quality of life score for nasal conjunctivitis［MD=0.43, 95%CI(-1.78, 2.65), P=0.70］ after treatment. No serious adverse reactions occurred after intradermal acupuncture treatment. Conclusion Using intradermal acupuncture to treat allergic rhinitis shows good curative effects and safety, and can reduce recurrence rates and nasal resistance, as well as improve quality of life. Due to the limits of our experimental design and issues related to the quantity and quality of original literature, the results of our meta-analysis still need to be further verified. In the future, relevant research should utilize other methodologies and strict experimental designs to provide more powerful, high-quality evidence-based data for the development of clinical diagnosis and treatment guidelines.

Key words: Intradermal acupuncture, Allergic rhinitis, Randomized controlled trial, Meta-analysis

CLC Number:

R276.1

ZHAI Rui, LI Yuan, YU Jinglong, CHEN Xi, ZHENG Youyou, LIU Zhaolan, WANG Junhong. Meta-analysis of clinical intradermal acupuncture efficacy for treatment of allergic rhinitis[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(3): 35-45.

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Meta-analysis of clinical intradermal acupuncture efficacy for treatment of allergic rhinitis

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[10]	ZHANG Yaqi, LIU Huimin, CAO Linman, WANG Ziyu, LIN Xu, LI Yanping, XUE Gang, WU Jingfang. Expression and significance of the MAPK,PI3K-AKT,NF-κB pathways of allergic rhinitis in mice [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 254-259.
[11]	LU Weili, JIANG Tao, LI Xianhua. Analysis of sIgE in polysensitized children with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 260-265.
[12]	HUANG Kaiyue, LI Xueqing, HAN Gouxin, ZHANG Qinxiu. Meta-analysis of acupoint catgut embedding in the treatment of allergic rhinitis based on the theory of “lung and spleen” [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 266-274.
[13]	ZHU Zhengru, ZHANG Xiaobing. Meta-analysis of the curative effect of traditional Chinese medicine decoction combined with conventional western medicine on allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 281-289.
[14]	LIU Shanshan, HAN Shujing, WANG Xiaoxu, LI Yanhong, NI Xin, ZHANG Jie. Hearing loss in children after bacterial meningitis: a systematic review and meta-analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 48-54.
[15]	PANG Chong, BIAN Sainan, ZHANG Bing, YIN Xu, LU Yingxia, YE Pengfei, WANG Zhan, ZHAO Jing, GAO Yan, GUAN Kai. Short-term effect of Dermatophagoides farinae specific sublingual immunotherapy for children with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 70-74.