山东大学耳鼻喉眼学报 ›› 2016, Vol. 30 ›› Issue (4): 98-100.doi: 10.6040/j.issn.1673-3770.0.2016.038

• 论著 • 上一篇    下一篇

中老年人真菌球性鼻窦炎临床特征及鼻内镜手术观察

刘英1,季青1,封新荣2,刘文2   

  1. 1.清华大学医院耳鼻喉科, 北京 100084;
    2.淄博市中心医院耳鼻咽喉-头颈外科, 山东 淄博 255000
  • 收稿日期:2016-01-25 出版日期:2016-08-16 发布日期:2016-08-16
  • 作者简介:刘英. E-mail:yingliu727@sina.com

Investigations on the clinical features and endoscopic sinus surgery for the elderly patients with fungus ball sinusitis.

LIU Ying1, JI Qing1, FENG Xinrong2, LIU Wen   

  1. 1. Department of Otolarynglogy, Tsinghua University Hospital, Beijing 100084, China;2. Department of Otolarynglogy Head and Neck Surgery, Central Hospital of Zibo, Zibo 255000, Shandong, China
  • Received:2016-01-25 Online:2016-08-16 Published:2016-08-16

摘要: 目的 探讨中老年人真菌球性鼻窦炎的临床特征、鼻内镜手术治疗的效果以及术后复发的处理。 方法 总结60例中老年真菌球性鼻窦炎患者的临床资料,分析该疾病的临床特征。患者均行鼻内镜手术治疗,手术前后行视觉模拟量表评分及鼻内镜检查评分。术后复发者行上颌窦冲洗。 结果 60例中临床主要症状依次为流涕、鼻塞、鼻腔异味、鼻涕倒流和涕中带血,常见体征为中鼻道狭窄及黏膜肿胀、脓性分泌物或干酪样物附着及息肉阻塞,76.92%具有典型的CT特征。术后视觉模拟量表及鼻内镜检查评分均较术前降低(P<0. 01),术后术腔完全恢复需6个月。4例复发患者通过上颌窦冲洗病情均完全控制。 结论 中老年真菌球性鼻窦炎临床特征及鼻腔检查结果各异,CT扫描对诊断有特殊价值。鼻内镜手术是治疗此病的有效手段,术后病情控制需6个月时间,上颌窦冲洗在治疗术后复发中起重要作用。

关键词: 临床特征, 真菌病, 鼻窦炎, 鼻内镜外科手术

Abstract: Objective To investigate the clinical characters of the elderly patients with fungus ball sinusitis, and assess the therapeutic effect of endoscopic sinus surgery and management for recurrence. Methods The clinical data of 60 cases were analyzed. All the patients were performed endoscopic sinus surgeries and Visual Analog Scale(VAS)and the endoscopic examination. Patients with post-operative recurrence were done the maxillary sinus irrigation. Results In this group, the main clinical symptoms were runny nose, stuffy nose, nasal odor, postnasal drip and drip with blood, and the common signs were the middle nasal meatus stenosis and mucosal swelling, purulent secretions or caseous matter attachment and nasal meat obstruction, 76.92 percent of the patients had typical CT features. Both the Visual Analog Scale(VAS)and the score of endoscopic examination after the surgery were significantly lower than those before the surgery(p-value <0.01). It took 6 months that the operated cavity fully recovered. 4 recurrent cases were under complete control through irrigation of maxillary sinus. Conclusion The clinical characters and nasal examination are different in elderly patients with fungus ball sinusitis, CT scanning has special value for diagnosis. Endoscopic sinus surgery is an efficient way for this disease and irrigation of the maxillary sinus plays an important role for post-operative recurrence.

Key words: Clinical characters, Endoscopic sinus surgical procedures, operative, Fungal disease, Nasosinusitis

中图分类号: 

  • R765.4
[1] Challa S, Uppin S G, Hanumanthu S, et al. Fungal rhinosinusitis: a clinicopathological study from South India[J]. EurArch Otorhinolaryngol, 2010, 267(8):1239- 1245.
[2] 中华耳鼻咽喉头颈外科杂志编辑委员会鼻科组,中华医学会耳鼻咽喉头颈外科学分会鼻科学组、慢性鼻.鼻窦炎诊断和治疗指南[J]. 中华耳鼻咽喉头颈外科杂志,2013,48(2):92-94.
[3] Van Cauwenberge P, Van Hoecke H, Bachert C. Pathogenesis of chronic rhinosinusitis[J]. Curr Allergy Asthma Rep, 2006, 6(6):487-494.
[4] 卿丽华.真菌性鼻-鼻窦炎发病相关因素及病理分型研究[J].重庆医科大学学报,2013,38(3):322-325.
[5] Adelson R T, Marple B F. Fungal rhinosinusitis: state-of-the-art diagnosis and treatment[J]. J Otolaryngol, 2005, 34(Suppl 1):18-23.
[6] 林琳,周霓,陈子松. 真菌性鼻-鼻窦炎189例临床分析[J]. 临床耳鼻咽喉头颈外科杂志, 2015,29(23):2064-2066. LIN Lin, ZHOU Ni, CHEN Zisong. Clinical analysis of fungal rhinosinusitis in 189 cases[J]. J Clin Otorhinolaryngol Head Neck Surg(China), 2015, 29(23):2064-2066.
[7] 李晓媛,陈晓栋,石照辉. 真菌球型鼻窦炎的临床及影像学特征[J]. 中国耳鼻咽喉头颈外科,2015,22(4):194-196. LI Xiaoxuan, CHEN Xiaodong, SHI Zhaohui. Clinical and imaging characteristics of fungal ball rhinosinusitis[J]. Chin Arch Otorhinolaryngol Head Neck Surg, 2015, 22(4):194-196.
[8] 李永奇,李源.真菌性鼻窦炎的诊治进展[J].国外医学耳鼻咽喉科分册,2003,27(3):162-166.
[9] 徐 晖,刘鹏.真菌球型鼻窦炎的研究进展[J].医学综述,2014,20,(13):2414-2416.
[10] 芦艳艳.真菌性鼻窦炎的诊治探讨[J].中国现代药物应用,2009, 3(7):20-21.
[11] 张健梅,李洁,文姝,等.鼻内镜手术治疗非侵袭性真菌性鼻窦炎[J].中国耳鼻咽喉头颈外科,2011,18(5):254-256. ZHANG Jianmei, LI Jie, WEN Shu, et al. Management of non-invasive fungal sinusitis with endoscopic sinus surgery[J]. Chin Arch Otorhinolaryngol Head Neck Surg, 2011, 18(5):254-256.
[12] 施思斯,张超,虞幼军,等. 111例非侵袭性真菌性鼻及鼻窦炎临床特征分析[J].临床耳鼻咽喉头颈外科杂志,2011,25(23):1084-1086. SHI Sisi, ZHANG Chao, YU Youjun, et al. Clinical analysis of 111 patients with non-invasive fungal rhino-sinusitis[J]. J Clin Otorhinolaryngol Head Neck Surg(China), 2011, 25(23):1084-1086.
[13] 熊颖,袁琨.非侵袭性真菌性鼻窦炎的诊疗方法及疗效分析[J].中华医院感染学杂志,2012,22(5):982-983.
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