儿童睡眠呼吸疾病的分类与治疗进展

doi:10.6040/j.issn.1673-3770.0.2016.405

摘要/Abstract

摘要： 儿童睡眠呼吸障碍(SDB)的人群发病率逐渐升高,而且儿童阻塞性睡眠呼吸暂停(OSA)是危害最大的一种睡眠呼吸紊乱性疾病,鼻塞、张口呼吸以及呼吸暂停缺氧等可影响小儿的颅面、鼻腔、生长及智力发育以及行为异常。因此,应尽早诊断和治疗儿童SDB,避免发生严重的并发症。合理有效地治疗可以减轻或完全缓解患儿打鼾、呼吸暂停、睡眠中的低氧血症和睡眠结构紊乱,提高患儿生活质量。

关键词: 病因学, 儿童, 分类, 睡眠呼吸暂停,阻塞性, 流行病学

Abstract: The incidence of sleep-disordered breathing(SDB)in children goes up gradually. However, obstructive sleep apnea(OSA)is the worst disorder of SDB diseases. Nasal obstruction, mouth breathing and hypoxia are known to cause different abnormalities that include craniofacial structure, nasal structure, growth, mental development and behaviors. Early diagnosis and treatment can prevent complications. The rational and effective treatment could relieve the snore, sleep apnea, hypoxemia and sleep disturbance, thus improve the childrens quality of life.

Key words: Etiology, Children, Classification, Epidemiology, Obstructive sleep apnea hypopnea syndrome

中图分类号:

R766.7

王岩. 儿童睡眠呼吸疾病的分类与治疗进展[J]. 山东大学耳鼻喉眼学报, 2016, 30(5): 5-8.

WANG Yan. Progress in the classification and treatment of sleep respiratory diseases in children.[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(5): 5-8.

参考文献

[1] Marcus C L. Diagnosis childhood obstructive sleep apnea syndrome[J]. Pediatrics, 2012, 130(3):e714-755.
[2] 刘玺诚,卢秀英,马瑜燕,等.北京地区2~6岁儿童睡眠障碍流行病学调查[J]. 中国儿童保健杂志,2004,12(4):301-303. LIU Xicheng, LU Xiuyig, MA Yuyan, et al. Epidemic survey of prevalence of children sleep disturbances aged 2-6 years old in Beijing[J]. Chin J Hild Health Care, 2004, 12(4):301-303.
[3] Redline S, Tishler P V, Schluchter M, et al. Risk factors for sleep-disordered breathing in children. Associations with obesity, race, and respiratory problems[J]. Am J Respir Crit Care Med, 1999, 159(5 Pt 1):1527-1532.
[4] Kang K T, Chiu S N, Weng W C, et al. Analysis of 24-hour ambulatory blood pressure monitoring in children with obstructive sleep apnea: a hospital-based study[J]. Medicine, 2015, 94(40): e1568.
[5] Wang Y, Wang J J, Zhao M Q, et al. Changes of serum brain-derived neurotrophic factor in children with obstructive sleep apnoea-hypopnoea syndrome following denotonsillectomy[J]. J Int Med Res, 2010, 38(6):1942-1951.
[6] 杨珊蕾,付丽,王岩,等.阻塞性睡眠呼吸暂停低通气综合征儿童认知行为异常与血清BDNF的相关性研究[J].山东大学耳鼻喉眼学报,2014,28(2):4-6. YANG Shanlei, FU Li, WANG Yan, et al. Relationship between the abnormal behavior and brain-derived neurotrophic factor in children with obstructive sleep apnea-hypopnea syndrome[J]. J Otolaryngol Ophthalmol Shandong Univ, 2014, 28(2):4-6.
[7] 张婵娟, 李延忠, 王岩. 睡眠呼吸暂停间歇性低氧对体外培养胚鼠皮质神经元的影响[J]. 临床耳鼻咽喉头颈外科杂志, 2015(9):845-848. ZHANG Chanjuan, LI Yanzhong, WANG Yan. Effect of intermittent hypoxia of sleep apnea on embryonic rat cortical neurons in vitro[J]. Clin J Otorhinolarynol Head Neck Surg, 2015(9):845-848.
[8] American Thoracic Society. Standards and indications for cardiopulmonary sleep studies in children[J]. Am J Respir Crit Care Med, 1996, 153(2):866-878.
[9] 中华耳鼻咽喉头颈外科杂志编委会,中华医学会耳鼻咽喉科学分会.儿童阻塞性睡眠呼吸暂停低通气综合征诊疗指南草案(乌鲁木齐)[J]. 中华耳鼻咽喉头颈外科杂志,2007,42(2):83-84.
[10] SA Bridgman Senior Lecturer in Surgical Trials Epidemiology, Dunn K M, Ducharme F. Surgery for obstructive sleep apnoea[J]. Cochrane Database Systematic Reviews, 2005, 30(4):75-88.
[11] Guilleminault C, Lee J H, Chan A. Pediatric obstructive sleep apnea syndrome[J]. Arch Pediatr Adolesc Med, 2005, 159(8):775-778.
[12] Mitchell R B. Adenotonsillectomy for obstructive sleep apneain children:outcome evaluated by pre-and postopera postoperative polysomnography[J]. Laryngoscope, 2007, 117(10):1844-1854.
[13] 邹娟娟,王岩,李延忠.不同术式对OSAHS患儿免疫功能的影响[J].临床耳鼻咽喉头颈外科杂志,2016,30(5):396-398. ZOU Juanjuan, WANG Yan, LI Yanzhong. Effects of different surgical procedures on immunity of children with obstructive sleep apnea hypopnea syndrome[J]. Clin J Otorhinolarynol Head Neck Surg, 2016, 30(5):396-398.
[14] Marcus C L, Brooks L J, Draper K A, et al. American Academy of Pediatrics. Diagnosis and management of childhood obstructive sleep apnea syndrome[J]. Pediatrics, 2012, 130(3):576-584.
[15] Chan C C K, Au C T, Lam H S, et al. Intranasal corticosteroids for mild childhood obstructive sleep apnea-a randomized, placebo-controlled study[J]. Sleep Medicine, 2015, 16(3):358-363.
[16] Massa F, Gonsalez S, Laverty A, et al. The use of nasal continuous positive airway pressure to treat obstructive sleep apnoea[J]. Arch Dis Child,2002, 87(5):438-443.

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