关于Alpha角0.5~0.8 mm的患者植入区域折射型人工晶状体的短期临床观察

doi:10.6040/j.issn.1673-3770.0.2021.251

摘要/Abstract

摘要： 目的研究Alpha角≤0.5 mm与Alpha角0.5~0.8 mm的患眼通过个性化手术设计植入区域折射型人工晶体的效果对比评估。方法患眼根据术前OPD检查的Alpha角数值分为观察组(Alpha角0.5~0.8 mm)和对照组(Alpha角≤0.5 mm),行超声乳化白内障摘除并植入区域折射型人工晶状体SBL-3,观察组采用个性化手术设计确定人工晶状体放置方向。对比两组术后1个月裸眼远视力(UDVA)、裸眼中视力(UIVA)、裸眼近视力(UNVA)以及4 mm瞳孔直径内全眼像差、角膜像差及眼内像差、对比两组术前术后Alpha角的变化。采用Mann-Whitney U检验方法对数据进行分析。结果观察组16例(16只眼),对照组17例(17只眼)。术后1个月2组的UDVA(P=0.286)、UIVA(P=0.318)、UNVA(P=0.449)差异无统计学意义;2组全眼及角膜的高阶像差(P全眼=0.368,P角膜=0.705)、总像差(P全眼=0.407,P角膜=0.387)、慧差(P全眼=0.957,P角膜=0.599)、三叶草差(P全眼=0.101,P角膜=0.576)、球差(P全眼=0.785,P角膜=0.443)的变化量差异无统计学意义;眼内高阶像差(P=0.387)、总像差(P=0.249)、慧差(P=0.33)、三叶草差(P=0.139)的变化量差异无统计学意义,眼内球差(P=0.007)的变化量差异有统计学意义;观察组(p=0.985)与对照组(P=0.890)患者术前术后Alpha角差异无统计学意义。结论 Alpha角0.5~0.8 mm的患者通过个性化设计放置区域折射型人工晶体SBL-3使视轴落在视远区可以达到与Alpha角≤0.5 mm的患者相同的手术效果。

关键词: Alpha角, 多焦点人工晶状体, 白内障, 高阶像差, 视力

Abstract: Objective To evaluate and compare the effect of regional refractive intraocular lens implantation through a personalized surgical design in eyes with an angle alpha of less than or equal to 0.5 mm and 0.5-0.8 mm. Methods The patients were divided into two groups based on OPD examination before the surgery. The observation and control groups included patients with an angle alpha of 0.5-0.8 mm and less than or equal to 0.5 mm, respectively. Phacoemul-sification cataract extraction and regional refractive intraocular lens SBL-3 implantation were performed. The observation group used an individualized surgical design to determine the direction of intraocular lens placement. We compared the uncorrected distance visual acuity(UDVA), uncorrected intermediate visual acuity(UIVA), uncorrected near visual acuity(UNVA), total eye aberration, corneal aberration, and intraocular aberration within a 4 mm pupil diameter between the two groups at one month after surgery. In addition, we compared the changes in angle alpha before and after surgery between the two groups. The Mann-Whitney U test was used to analyze the data. Results The observation and control groups comprised 16 cases(16 eyes)and 17 cases(17 eyes), respectively. There was no statistical difference between the two groups of patients in terms of UDVA(P=0.286), UIVA(P=0.318), UNVA(P=0.449). High-order aberrations(P_{whole eye}=0.368,P_{cornea changes}=0.705), all intraocular aberration(P_{whole eye}=0.407,P_{cornea changes}=0.387), coma aberration(P_{whole eye}=0.957,P_{cornea changes}=0.599), intraocular clover aberration(P_{whole eye}=0.101, P_{cornea changes}=0.576), and spherical aberration(P_{whole eye}=0.785, P_{comea changes}=0.443)of the whole eye and cornea changes were not statistically significant; intraocular high-aberrations(P=0.387), intraocular clover aberration(P=0.139), all intraocular aberration(P=0.249), and coma aberration(P=0.33)were not statistically significant; intraocular spherical aberration(P=0.007)was statistically significant. There was no significant difference in angle alpha between the observation and control groups(P=0.985, P=0.890)before and after surgery. Conclusion Patients with an angle alpha of 0.5-0.8 mm can achieve the same surgical effect as that of patients with angle alpha less than or equal to 0.5 mm, by rotating the lens SBL-3 to make the visual axis land in the distal region.

Key words: Angle alpha, Multifocal intraocular lens, Cataract, Higher-order aberration, Vision

中图分类号:

R765.21

孙璐,张顺华,吴昱舟,陈露璐,曹迪,干霖洋. 关于Alpha角0.5~0.8 mm的患者植入区域折射型人工晶状体的短期临床观察[J]. 山东大学耳鼻喉眼学报, 2022, 36(6): 32-37.

SUN Lu, ZHANG Shunhua, WU Yuzhou, CHEN Lulu, CAO Di, GAN Linyang. Short-term clinical outcomes of regional refractive intraocular lens implantation in patients with an angle alpha of 0.5-0.8 mm[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(6): 32-37.

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