山东大学耳鼻喉眼学报

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普米克令舒在功能性鼻内镜手术中的应用及疗效观察

俞晨杰,陈 峰,戴艳红,王俊国,顾亚军,高 下   

  1. 南京大学医学院附属鼓楼医院耳鼻咽喉-头颈外科, 江苏 南京 210008
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-04-24 发布日期:2007-04-24
  • 通讯作者: 俞晨杰

Effect of Pulmicort respule on rehabilitation after functional endosocopic sinus surgery

YU Chen-jie,CHEN Feng,DAI Yan-hong,WANG Jun-guo,GU Ya-jun,GAO Xia   

  1. Department of Otorhinolaryngology and Head & Neck Surgery,Affiliated Drum Tower Hospital,Medical School of Nanjing University,Nanjing 210008,Jiangsu,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-04-24 Published:2007-04-24
  • Contact: YU Chen-jie

摘要: 目的:探讨普米克令舒对功能性鼻内窥镜手术后术腔恢复的影响。方法:27例慢性鼻-鼻窦炎伴鼻息肉Ⅱ型Ⅲ期或Ⅲ型患者,采用双侧鼻腔自身对照,常规选取左侧鼻腔为普米克令舒治疗组,右侧鼻腔为对照组。手术结束前,用含普米克令舒混悬液的明胶海绵覆盖术腔。留置筛窦术腔膨胀海绵1周,术后每次换药予以含普米克令舒混悬液的明胶海绵覆盖筛窦术腔。记录患者术腔黏膜的转归过程。结果:普米克令舒治疗组术后2个月内各鼻窦分泌物逐渐减少,鼻腔黏膜肿胀反应轻,上皮化时间大大缩短,与对照组相比差异有统计学意义(P<0.01)。治疗组92.6%的患者达到治愈的标准,疗效满意,与对照组85.2%的治愈率差异无统计学意义(P>0.05)。结论:功能性鼻内窥镜术后局部使用普米克令舒能有效减轻术腔黏膜的炎症状态,加快术腔上皮化进程,促进黏膜的顺利转归,但对治愈率无明显影响。

关键词: 鼻息肉, 鼻窦炎, 普米克令舒, 内窥镜外科手术

Abstract: Objective: To investigate the effect of Pulmicort respule on rehabilitation of patients subjected to functional endoscopic sinus surgery(FESS). Methods: Twenty-seven patients suffering from chronic rhinosinusitis of polyposis type Ⅱ stage Ⅲ or type Ⅲ were enrolled in this selfcontrolled study. The left nostril was subjected to Pulmicort respule using a swell sponge just before the end of the surgery, the right, however, was not. The swell sponges were kept in the nostril for 1 week, and absorbable gelatin sponges with Pulmicort respule were given into the same nostril each time when the patients came in the following stage. The transitionary process of the mucosa was determined. Results: The excretions were decreased, the mucosa intumescence was diminished, and epithelization was established in a shorter time in the experimental group than in the control group. The cure rate was 92.6% in the experimental group and 85.2% in the control group (P>0.05). There were no significant differences between the two groups. Conclusion: Using Pulmicort respule locally is a benefit for relieving mucosa inflammation, shortening the stage of epithelization, and accelerating the recovery of mucosa after FESS.

Key words: Nasal polyps, Sinusitis, Pulmicort respule, Endoscopic surgical procedures, operative

中图分类号: 

  • R765.21
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