咽喉部鳞状细胞癌细胞系

doi:10.6040/j.issn.1673-3770.0.2020.478

摘要/Abstract

摘要： 咽喉部鳞状细胞癌是头颈外科常见恶性肿瘤,头颈部解剖结构复杂,原发部位不同的鳞状细胞癌发病率、诊疗方案不同,其发生的分子机制也可能存在差异。因此,选择适合的咽喉部鳞状细胞癌细胞系对于研究者选择适合的临床前研究模型,以及更好地理解肿瘤发生发展机制具有重要意义。总结了鼻咽、口咽、喉咽、喉四个解剖部位的鳞状细胞癌细胞系,以望对研究者选择适当的细胞系作为研究对象提供参考。

关键词: 鼻咽癌, 口咽癌, 下咽癌, 喉癌, 鳞状细胞癌细胞系

Abstract: Larynx squamous cell carcinoma is a common malignant tumor of the head and neck region. The head and neck have complicated anatomical structure, and squamous cell carcinomas with different primary sites have different incidences, strategies of diagnosis and therapy, and even molecular pathogeneses. Therefore, selecting the suitable squamous cell carcinoma cell lines is important for researchers to determine appropriate preclinical research models and to have a better understanding of the mechanisms of tumorigenesis and progression. To provide a reference for researchers, this study summarizes the currently available squamous cell carcinoma cell lines originating from the nasopharynx, oropharynx, laryngopharynx and larynx.

Key words: Nasopharynx Carcinoma, Oropharynx Carcinoma, laryngopharynx Carcinoma, larynx carcinoma, Cell lines of squamous cell carcinoma

中图分类号:

R739.6

冯成敏,敬一丹,刘海,王冰. 咽喉部鳞状细胞癌细胞系[J]. 山东大学耳鼻喉眼学报, 2021, 35(6): 113-124.

FENG Chengmin, JIN Yidan,LIU Hai, WANG Bing. A review of squamous cell lines originating from the nasopharynx, oropharynx, laryngopharynx and larynx[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 113-124.

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