山东大学耳鼻喉眼学报 ›› 2021, Vol. 35 ›› Issue (6): 113-124.doi: 10.6040/j.issn.1673-3770.0.2020.478

• • 上一篇    下一篇

咽喉部鳞状细胞癌细胞系

冯成敏1, 2,敬一丹1, 2，刘海2,王冰3   

  1. 1. 川北医学院附属医院 耳鼻咽喉头颈外科, 四川 南充 637000;
    2. 川北医学院 临床医学系, 四川 南充 637000;
    3. 川北医学院医学影像四川省重点实验室, 四川 南充 637000
  • 发布日期:2021-12-10
  • 通讯作者: 刘海. E-mail:liuhai100@sina.com
  • 基金资助:
    南充市2019年市校合作科研专项(川北医学院)基础课题研究(19SXHZ0072);中央引导地方科技发展专项自由探索类基础研究(2020ZYD056);四川省医学(青年创新)科研课题(S19055)

A review of squamous cell lines originating from the nasopharynx, oropharynx, laryngopharynx and larynx

FENG Chengmin1,2, JIN Yidan1,2,LIU Hai2, WANG Bing3   

  1. 1. Department of Otorhinolaryngology & Head Neck Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong 63700, Sichuan, China;
    2. Department of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, Sichuan, China;
    3. Medical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong 637000, Sichuan, China
  • Published:2021-12-10

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摘要： 咽喉部鳞状细胞癌是头颈外科常见恶性肿瘤,头颈部解剖结构复杂,原发部位不同的鳞状细胞癌发病率、诊疗方案不同,其发生的分子机制也可能存在差异。因此,选择适合的咽喉部鳞状细胞癌细胞系对于研究者选择适合的临床前研究模型,以及更好地理解肿瘤发生发展机制具有重要意义。总结了鼻咽、口咽、喉咽、喉四个解剖部位的鳞状细胞癌细胞系,以望对研究者选择适当的细胞系作为研究对象提供参考。

关键词: 鼻咽癌, 口咽癌, 下咽癌, 喉癌, 鳞状细胞癌细胞系

Abstract: Larynx squamous cell carcinoma is a common malignant tumor of the head and neck region. The head and neck have complicated anatomical structure, and squamous cell carcinomas with different primary sites have different incidences, strategies of diagnosis and therapy, and even molecular pathogeneses. Therefore, selecting the suitable squamous cell carcinoma cell lines is important for researchers to determine appropriate preclinical research models and to have a better understanding of the mechanisms of tumorigenesis and progression. To provide a reference for researchers, this study summarizes the currently available squamous cell carcinoma cell lines originating from the nasopharynx, oropharynx, laryngopharynx and larynx.

Key words: Nasopharynx Carcinoma, Oropharynx Carcinoma, laryngopharynx Carcinoma, larynx carcinoma, Cell lines of squamous cell carcinoma

中图分类号: 

  • R739.6
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